South African Herbal Science and Medicine Institute (SAHSMI)
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Bioassay-guided fractionation leads to the detection of cholic acid generated by the rare thalassomonas sp.
(Pubmed, 2023)Bacterial symbionts of marine invertebrates are rich sources of novel, pharmaceutically relevant natural products that could become leads in combatting multidrug-resistant pathogens and treating disease. In this study, ... -
In vitro evaluation of the antiproliferative activity of Carpobrotus edulis on human neuroblastoma cells
(Elsivier, 2021)Neuroblastoma is a solid neuroendocrine tumour located outside the cranial cavity and contributes about 15% of all cancer‑associated deaths in children. Treatment of neuroblastoma is quite challenging and involves the use ... -
Sutherlandia frutescens: The meeting of science and traditional knowledge
(Mary Ann Liebert, 2013)Sutherlandia frutescens (L.) R.Br. (syn. Lessertia frutescens (L.) Goldblatt and J.C. Manning) is an indigenous medicinal plant extensively used in South Africa to treat a variety of health conditions. It is a fairly ... -
Photosynthetic adaptation of two semi-arid species of Gethyllis (Kukumakranka) to drought-and-shade stress
(Elsevier, 2013)Gethyllis multifolia and Gethyllis villosa are winter-growing, summer-blooming, deciduous and bulbous geophytes that grow naturally in the semi-arid ‘Succulent Karoo Biome’ of South Africa. G. multifolia is threatened ... -
Challenges relating to comparison of flavonoid glycosides dissolution profiles from Sutherlandia frutescens products
(De Gruyter Open, 2017)Unlike the case of conventional drug formulations, dissolution tests have hitherto not been required for herbal medicinal products commercially available in South Africa. This study investigated dissolution of the South ... -
Antimicrobial activities of a novel biflavonoid and other constituents from Rhus natalensis
(Academic Journals, 2013)Phytochemical studies on Rhus natalensis root bark collected from Kenya led to the isolation and identification of a new biflavonoid (3-(1-(2,4-dihydroxyphenyl)-3,3-bis(4-hydroxyphenyl)-1-oxopropan-2- yl)-7-methoxy-4H-ch ... -
Some alkaloids and flavonoids from Cissampelos capensis
(Academic Journals, 2015)Following the screening of several plant species from an inventory of common medicinal plants from South Africa for medicinal properties, Cissampelos capensis was selected for further investigation due to its interesting ... -
Phytochemical screening and biological activity studies of five South African indigenous medicinal plants
(Academic Journals, 2010)Different extracts and fractions of five selected indigenous South African medicinal plants, namely, Cissampelos capensis, Geranium incanum and three Gethyllis species, were subjected to phytochemical screening and testing ... -
HPLC determination of selected flavonoid glycosides and their corresponding aglycones in Sutherlandia frutescens materials
(OMICS, 2016)Sutherlandia frutescens is a popular South African plant commercially available in a range of formulations. However, reference standards for quality and stability assessment are lacking. This work reports the development and ...
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