Browsing Statistics and Population Studies by Author "Seedat, Soraya"
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BDNF Val66Met and DRD2 Taq1A polymorphisms interact to influence PTSD symptom severity: A preliminary investigation in a South African population
Hemmings, Sian M.J.; Martin, Lindi I.; Klopper, Marisa; van der Merwe, Lize; Aitken, Lisa; de Wit, Erika; Black, Gillian F.; Hoal, Eileen G.; Walzl, Gerhard; Seedat, Soraya (Elsevier, 2013)BACKGROUND: We evaluated the role that selected variants in serotonin transporter (5-HTT), dopamine receptor 2 (DRD2) and brain-derived neurotrophic factor (BDNF) genes play in PTSD symptom severity in an at-risk population. ... -
BDNF Val66Met modifies the risk of childhood trauma on obsessive-compulsive disorder
Hemmings, Sian Megan Joanna; Lochner, Christine; van der Merwe, Lize; Cath, Danielle C.; Seedat, Soraya; Stein, Dan J. (Elsevier, 2013)Childhood trauma has been linked to the development of later psychopathology, including obsessive-compulsive disorder (OCD). Although evidence exists to suggest that genetic and environmental factors are involved in the ...