Browsing Research Articles (SANBI) by Author "Syce, James"
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Predictive classifier models built from natural products with antimalarial bioactivity using machine learning approach
Egieyeh, Samuel; Syce, James; Malan, Sarel F.; Christoffels, Alan (Public Library of Science, 2018)In view of the vast number of natural products with potential antiplasmodial bioactivity and cost of conducting antiplasmodial bioactivity assays, it may be judicious to learn from previous antiplasmodial bioassays and ... -
Prioritization of anti-malarial hits from nature: Chemo-informatic profiling of natural products with in vitro antiplasmodial activities and currently registered anti-malarial drugs
Egieyeh, Samuel Ayodele; Syce, James; Malan, Sarel F. (BMC, 2016)A large number of natural products have shown in vitro antiplasmodial activities. Early identification and prioritization of these natural products with potential for novel mechanism of action, desirable pharmacokinetics ...