Research Articles (SANBI): Recent submissions
Now showing items 121-127 of 127
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Molecular evolution of key receptor genes in primates and non-human primates
(Science Publishing Group, 2014)African primates remain an unexplored source of information required to complete the origin and evolution of many human pathogens. Current studies have shown the importance of several receptor human genes implicated in ... -
Human African trypanosomiasis research gets booost: unravelling the tsetse Genome
(PLOS, 2014)Human African trypanosomiasis (HAT), also known as sleeping sickness, is a neglected disease that impacts 70 million people distributed over 1.55 million km2 in sub-Saharan Africa. Trypanosoma brucei gambiense accounts for ... -
A glance at quality score: implication for de novo transcriptome reconstruction of Illumina reads
(Frontiers, 2014)Downstream analyses of short-reads from next-generation sequencing platforms are often preceded by a pre-processing step that removes uncalled and wrongly called bases. Standard approaches rely on their associated base ... -
Evolution and structural analysis of Glossina morsitans (Diptera; Glossinidae) Tetraspanins
(MDPI, Basel, Switzerland, 2014)Tetraspanins are important conserved integral membrane proteins expressed in many organisms. Although there is limited knowledge about the full repertoire, evolution and structural characteristics of individual members ... -
Odorant and gustatory receptors in the tsetse fly Glossina morsitans morsitans
(PLOS, 2014)Tsetse flies use olfactory and gustatory responses, through odorant and gustatory receptors (ORs and GRs), to interact with their environment. Glossina morsitans morsitans genome ORs and GRs were annotated using homologs ... -
International Glossina Genome Initiative 2004-2014: a driver for post-genomic era research on the African continent
(PLOS, 2014)Human African trypanosomiasis (HAT), also known as sleeping sickness, is a neglected disease that impacts 70 million people distributed over 1.55 million km2 in sub- Saharan Africa and includes at least 50% of the population ... -
Inferring bona fide transfrags in RNA-Seq derived-transcriptome assemblies of non-model organisms
(BioMed Central, 2015)Background: De novo transcriptome assembly of short transcribed fragments (transfrags) produced from sequencing-by-synthesis technologies often results in redundant datasets with differing levels of unassembled, partially ...