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Now showing items 5750-5769 of 7987
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Protein profiling in unlocking the basis of varicocele-associated infertility
(Blackwell Publishing Ltd, 2021)Varicocele is one of the major causes of male infertility and has a negative impact on spermatogenesis. The conventional semen analysis does not reveal the underlying subcellular mechanisms associated with defects in ... -
Proteomic analysis of grape berry cell cultures reveals that developmentally regulated ripening related processes can be studied using cultured cells
(Public Library of Science, 2011)This work describes a proteomics profiling method, optimized and applied to berry cell suspensions to evaluate organ-specific cultures as a platform to study grape berry ripening. Variations in berry ripening within a ... -
Proteomic identification and meta-analysis in salvia hispanica RNA-seq de novo assemblies
(2021)While proteomics has demonstrated its value for model organisms and for organisms with mature genome sequence annotations, proteomics has been of less value in nonmodel organisms that are unaccompanied by genome sequence ... -
Proteomic mechanisms of drug resistance in Candida cell membrane fractions
(International Association for Dental Research, 2014)INTRODUCTION: The African continent has the highest burden of HIV infection, accounting for approximately 65% of new infections globally. Oral candidiasis is a major cause of increased morbidity in HIV-infected individuals ... -
Proteomics analysis of the p.G849D variant in neurexin 2 alpha may reveal insight into Parkinson’s disease pathobiology
(Frontiers, 2022)Parkinson’s disease (PD), the fastest-growing neurological disorder globally, has a complex etiology. A previous study by our group identified the p.G849D variant in neurexin 2 (NRXN2), encoding the synaptic protein, ... -
Proteomics and metabolomics — Current and future perspectives in clinical andrology
(Blackwell Publishing Ltd, 2021)Proteomics and metabolomics are emerging as promising tools to investigate the molecular mechanisms associated with male infertility. Proteins and metabolites play a pivotal role in regulating the molecular pathways ... -
Proteomics of drug-resistant HIV-associated candidiasis
(University of the Western Cape, 2015)Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ... -
Protocol for a scoping review of existing policies on the prevention and control of obesity across countries in Africa
(BMJ Publishing Group, 2017)INTRODUCTION: The obesity epidemic is a public health challenge for all, including low-income countries. The behavioural patterns known to contribute to the rise in obesity prevalence occur in an environmental context which ... -
Protocol for assessing feasibility, acceptability and fidelity of screening for antenatal depression (FAFSAD) by midwives in Blantyre District, Malawi
(Springer Nature, 2021)Depression is often underdiagnosed by treating health professionals. This is a situation in Malawi where there is no routine screening of depression at antenatal clinics. Recently, a Screening Protocol for Antenatal Depression ... -
Protocol for management of odontogenic keratocysts considering recurrence according to treatment methods
(Korean Association of Oral and Maxillofacial Surgeons, 2020)The management of odontogenic keratocysts (OKC) remains a hotly debated topic in oral and maxillofacial surgery. Despite numerous studies and systematic reviews on treatment options, there is a lack of consensus and no ... -
Protocol for systematic review of school-based interventions to prevent and control obesity in African learners
(BMJ Publishing Group, 2017)INTRODUCTION: The increasing prevalence of obesity and overweight in childhood in developing countries is a public health concern to many governments. Schools play a significant role in the obesity epidemic as well as ... -
Provenance and tectonic setting of the Paleozoic Tamatán Group, NE Mexico: Implications for the closure of the Rheic Ocean
(Elsevier, 2021)The Huizachal–Peregrina Anticlinorium in northeastern Mexico comprises a wide variety of Precambrian and Paleozoic basement units. In this work, Silurian-to-Permian unmetamorphosed siliciclastic successions (i.e., Cañón ... -
Provenance of metasedimentary rocks of the western Dom Feliciano Belt in Uruguay: Insights from U–Pb detrital zircon geochronology, Hf and Nd model ages, and geochemical data
(Elsevier, 2021)New isotopic and geochemical data for the Paleo- Meso- and Neoproterozoic metasedimentary cover of the southern Dom Feliciano Belt (Brasiliano/Pan-African) are presented and evaluated combined with published information. ... -
Providing for the unwanted in a time of crisis: The socio-economic rights of migrant workers in South Africa under covid- 19 pandemic
(Juta, 2020)Migrants are amongst the most vulnerable groups in South Africa. They are often subjected to harsh forms of discrimination and excluded from government policy considerations. They have not fared differently under the ... -
Provision of inpatient rehabilitation and challenges experienced with participation post discharge: quantitative and qualitative inquiry of African stroke patients
(BioMed Central, 2015)BACKGROUND: The provision of rehabilitation differs between developed and developing countries, this could impact on the outcomes of post stroke rehabilitation. The aim of this paper is to present provision of in-patient stroke ... -
Provision of syndromic treatment of sexually transmitted infections by community pharmacists: a potentially underutilized HIV prevention strategy
(Lippincott, Williams & Wilkins, 2003)Background: Sexually transmitted infections (STIs) are known risk factors for HIV infection. Goal: The goal of this study was to assess the current and potential future role that community pharmacists in Western Cape, South ... -
Proximate determinants of fertility in Ethiopia: comparative analysis of the 2005 and 2011 DHS
(SAGE Publications, 2017)Fertility is one of the elements in population dynamics that makes a significant contribution towards changing population size and structure over time. In Ethiopia, for the last 10 years the total fertility rate (TFR) has ... -
Pseudocapacitive effects of multi-walled carbon nanotubes-functionalised spinel copper manganese oxide
(MDPI, 2022)Spinel copper manganese oxide nanoparticles combined with acid-treated multi-walled carbon nanotubes (CuMn2O4/MWCNTs) were used in the development of electrodes for pseudocapacitor applications. The CuMn2O4/MWCNTs ... -
PSRJ1910–5959A: A rare gravitational laboratory for testing white dwarf models
(EDP Sciences, 2023)Context. PSR J1910-5959A is a binary millisecond pulsar in a 0.837 day circular orbit around a helium white dwarf (HeWD) companion. The position of this pulsar is 6.3 arcmin (∼74 core radii) away from the optical centre ... -
Psychological capital: The antidote for the consequences of organisational citizenship behaviour in industry 4.0 workplace
(Springer, Cham, 2021)Managing the associated consequences of the increasing demand for organisational citizenship behaviour (OCB) is one of the common phenomena of concerns among professionals and scholars in the fields of Industrial/Organisational ...