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Molecular dynamic simulations to investigate the structural impact of known drug resistance mutations on HIV-1C integrase-dolutegravir binding
(Public Library of Science, 2020)
Resistance associated mutations (RAMs) threaten the long-term success of combination antiretroviral therapy (cART) outcomes for HIV-1 treatment. HIV-1 Integrase (IN) strand transfer inhibitors (INSTIs) have proven to be a ...
Dual use school community libraries: expedient compromise or imaginative solution?
(University of Alberta Libraries, 2021-02)
The paper reports on a research project in a group of six dual use school community
libraries in a rural region of South Africa1. The six dual use libraries were established with donor
funding in 2001 as part of a larger ...
Looking back to look forward: a review of human resources for health governance in South Africa from 1994 to 2018
(Springer Nature, 2020)
While South Africa has had a fairly consistent record of producing national-level strategic plans for human resources for health in the past 25 years, the country continues to face major problems of affordability, availability, ...
Use of social media platforms by manufacturers to market breast-milk substitutes in South Africa
(BMJ Publishing Group, 2020)
In South Africa (SA), exclusive breast feeding remains rare, with breast-milk substitutes (BMS) commonly being used in ways that are detrimental to infant and young child nutrition, health and survival. The use of internet, ...
Desperate times call for desperate measures: Adapting antiretroviral service delivery in the context of the COVID-19 pandemic
(SAMA, 2020)
On 23 March 2020, President Cyril Ramaphosa
announced a nation-wide lockdown to help curb the spread of the
COVID-19 epidemic in South Africa (SA). While these containment
measures are considered to have limited the ...
Water, sanitation, and hygiene (WASH) factors associated with growth between birth and 1 year of age in children in Soweto, South Africa: Results from the Soweto Baby WASH study
(IWA Publishing, 2020)
Interventions to reduce undernutrition and improve child growth have incorporated improved water, sanitation, and hygiene (WASH) as part of disease transmission prevention strategies. Knowledge gaps still exist, namely, ...
Towards achieving the 90–90–90 HIV targets: Results from the south African 2017 national HIV survey
(Springer Nature, 2020)
Background: Measuring progress towards the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90–90–90 treatment targets is key to assessing progress towards turning the HIV epidemic tide. In 2017, the UNAIDS model estimated ...
Unspoken inequality: How COVID-19 has exacerbated existing vulnerabilities of asylum-seekers, refugees, and undocumented migrants in South Africa
(Springer Nature, 2020)
An estimated 2 million foreign-born migrants of working age (15-64) were living in South Africa (SA) in 2017. Structural and practical xenophobia has driven asylum-seekers, refugees, and undocumented migrants in SA to ...
Trace elements risk assessment for consumption of wild mussels along South Africa coastline
(Elsevier, 2021)
The study aimed to contribute to the scarce data on concentrations in the soft tissue of wild mussels growing in coastal cities of South Africa. The intake of 26 micro and macroelements was estimated. The mass fractions ...
Exposure of children to unhealthy food and beverage advertisements in South Africa
(MPDI, 2021)
Television (TV) is a powerful medium for marketing food and beverages. Food and beverage marketers tend to use this medium to target children with the hope that children will in turn influence their families’ food choices. ...