Browsing Faculty of Natural Sciences by Title
Now showing items 1904-1923 of 2571
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Protein interaction networks as metric spaces: A novel perspective on distribution of hubs
(BMC, 2014)In the post-genomic era, a central and overarching question in the analysis of protein-protein interaction networks continues to be whether biological characteristics and functions of proteins such as lethality, physiological ... -
Protein profiling in unlocking the basis of varicocele-associated infertility
(Blackwell Publishing Ltd, 2021)Varicocele is one of the major causes of male infertility and has a negative impact on spermatogenesis. The conventional semen analysis does not reveal the underlying subcellular mechanisms associated with defects in ... -
Proteomic analysis of grape berry cell cultures reveals that developmentally regulated ripening related processes can be studied using cultured cells
(Public Library of Science, 2011)This work describes a proteomics profiling method, optimized and applied to berry cell suspensions to evaluate organ-specific cultures as a platform to study grape berry ripening. Variations in berry ripening within a ... -
Proteomic identification and meta-analysis in salvia hispanica RNA-seq de novo assemblies
(2021)While proteomics has demonstrated its value for model organisms and for organisms with mature genome sequence annotations, proteomics has been of less value in nonmodel organisms that are unaccompanied by genome sequence ... -
Proteomic mechanisms of drug resistance in Candida cell membrane fractions
(International Association for Dental Research, 2014)INTRODUCTION: The African continent has the highest burden of HIV infection, accounting for approximately 65% of new infections globally. Oral candidiasis is a major cause of increased morbidity in HIV-infected individuals ... -
Proteomics analysis of the p.G849D variant in neurexin 2 alpha may reveal insight into Parkinson’s disease pathobiology
(Frontiers, 2022)Parkinson’s disease (PD), the fastest-growing neurological disorder globally, has a complex etiology. A previous study by our group identified the p.G849D variant in neurexin 2 (NRXN2), encoding the synaptic protein, ... -
Proteomics and metabolomics — Current and future perspectives in clinical andrology
(Blackwell Publishing Ltd, 2021)Proteomics and metabolomics are emerging as promising tools to investigate the molecular mechanisms associated with male infertility. Proteins and metabolites play a pivotal role in regulating the molecular pathways ... -
Proteomics of drug-resistant HIV-associated candidiasis
(University of the Western Cape, 2015)Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ... -
Provenance and tectonic setting of the Paleozoic Tamatán Group, NE Mexico: Implications for the closure of the Rheic Ocean
(Elsevier, 2021)The Huizachal–Peregrina Anticlinorium in northeastern Mexico comprises a wide variety of Precambrian and Paleozoic basement units. In this work, Silurian-to-Permian unmetamorphosed siliciclastic successions (i.e., Cañón ... -
Provenance of metasedimentary rocks of the western Dom Feliciano Belt in Uruguay: Insights from U–Pb detrital zircon geochronology, Hf and Nd model ages, and geochemical data
(Elsevier, 2021)New isotopic and geochemical data for the Paleo- Meso- and Neoproterozoic metasedimentary cover of the southern Dom Feliciano Belt (Brasiliano/Pan-African) are presented and evaluated combined with published information. ... -
Provision of syndromic treatment of sexually transmitted infections by community pharmacists: a potentially underutilized HIV prevention strategy
(Lippincott, Williams & Wilkins, 2003)Background: Sexually transmitted infections (STIs) are known risk factors for HIV infection. Goal: The goal of this study was to assess the current and potential future role that community pharmacists in Western Cape, South ... -
Proximate determinants of fertility in Ethiopia: comparative analysis of the 2005 and 2011 DHS
(SAGE Publications, 2017)Fertility is one of the elements in population dynamics that makes a significant contribution towards changing population size and structure over time. In Ethiopia, for the last 10 years the total fertility rate (TFR) has ... -
Pseudocapacitive effects of multi-walled carbon nanotubes-functionalised spinel copper manganese oxide
(MDPI, 2022)Spinel copper manganese oxide nanoparticles combined with acid-treated multi-walled carbon nanotubes (CuMn2O4/MWCNTs) were used in the development of electrodes for pseudocapacitor applications. The CuMn2O4/MWCNTs ... -
PSRJ1910–5959A: A rare gravitational laboratory for testing white dwarf models
(EDP Sciences, 2023)Context. PSR J1910-5959A is a binary millisecond pulsar in a 0.837 day circular orbit around a helium white dwarf (HeWD) companion. The position of this pulsar is 6.3 arcmin (∼74 core radii) away from the optical centre ... -
Psychosocial reintegration following traumatic spinal cord injury in South Africa: The influence of employment, injury characteristics and living situation
(The Journal of Spinal Cord Medicine,, 2022)1Department of Health and Rehabilitation Sciences, Division of Physiotherapy, Stellenbosch University, Cape Town, South Africa, 2Department of Physiotherapy, University of the Western Cape, Cape Town, South Africa Objectives: ... -
Pt decorated amorphous RuIr alloys as high efficiency electrocatalyst for methanol oxidation
(The Electrochemical Society, 2012)This study focuses primarily on improving the utilization and activity of anodic catalysts for methanol electro-oxidation. The Direct Methanol Fuel Cell (DMFC) anodic catalyst, a carbon supported Pt decorated amorphous ... -
Pt-Sn/C as a possible methanol-tolerant cathode catalyst for DMFC
(Springer Verlag, 2013)An effective method was developed for preparing highly dispersed nano-sized Pt–Sn/C electrocatalyst synthesised by a modified polyol reduction method. From XRD patterns, the Pt–Sn/C peaks shifted slightly to lower 2θ angles ... -
Pulmonary effects and disposition of luteolin and Artemisia afra extracts in isolated perfused lungs
(Elsevier, 2013)ETHNOPHARMACOLOGICAL RELEVANCE: Artemisia afra (Asteraceae) is a traditional medicinal plant frequently used in steam inhalation form to treat respiratory conditions. AIM OF THE STUDY: Quantify luteolin content in Artemisia ... -
Pulsar scintillation studies with LOFAR I. The census
(Hans Publishers, 2022)Interstellar scintillation (ISS) of pulsar emission can be used both as a probe of the ionized interstellar medium (IISM) and cause corruptions in pulsar timing experiments. Of particular interest are so-called scintillation ... -
Pulsars with NenuFAR: Backend and pipelines
(EDP Sciences, 2021)Context. NenuFAR (New extension in Nançay upgrading LOFAR) is a new radio telescope developed and built on the site of the Nançay Radio Observatory. It is designed to observe the largely unexplored frequency window from ...