Browsing Faculty of Natural Sciences by Title
Now showing items 2244-2263 of 2571
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Structural Insights and Docking Analysis of Adamantane-Linked 1,2,4-Triazole Derivatives as Potential 11 -HSD1 Inhibitors
(Molecules, 2021)The solid-state structural analysis and docking studies of three adamantane-linked 1,2,4- triazole derivatives are presented. Crystal structure analyses revealed that compound 2 crystallizes in the triclinic P-1 space ... -
Structural rearrangements maintain the Glycan Shield of an HIV-1 envelope trimer after the loss of a glycan
(Nature Research, 2018)The HIV-1 envelope (Env) glycoprotein is the primary target of the humoral immune response and a critical vaccine candidate. However, Env is densely glycosylated and thereby substantially protected from neutralisation. ... -
Structure and biosynthesis of carotenoids produced by a novel Planococcus sp. isolated from South Africa
(BMC, 2022)The genus Planococcus is comprised of halophilic bacteria generally reported for the production of carotenoid pigments and biosurfactants. In previous work, we showed that the culturing of the orange-pigmented Planococcus ... -
Structure and biosynthesis of carotenoids produced by a novel planococcus sp. isolated from South Africa
(Microb Cell Fac, 2022)Background: The genus Planococcus is comprised of halophilic bacteria generally reported for the production of carotenoid pigments and biosurfactants. In previous work, we showed that the culturing of the orange-pigmented ... -
Structure and functional characterization of pyruvate decarboxylase from Gluconacetobacter diazotrophicus
(BioMed Central, 2014)BACKGROUND: Bacterial pyruvate decarboxylases (PDC) are rare. Their role in ethanol production and in bacterially mediated ethanologenic processes has, however, ensured a continued and growing interest. PDCs from ... -
Structure based identification of novel inhibitors against ATP synthase of Mycobacterium tuberculosis: A combined in silico and in vitro study
(International Journal of Biological Macromolecules, 2019)The shortcomings of conventional tuberculosis treatments resulting from the development of drug resistance in Mycobacteriumtuberculosis drive a need for the formulation of novel therapeutic agents. The diarylquinoline ... -
A structure function analysis of vst-cosmos agn
(EDP Sciences, 2022)We present our sixth work in a series dedicated to variability studies of active galactic nuclei (AGN), based on the survey of the COSMOS field by the VLT Survey Telescope (VST). Its 54 r-band visits over 3.3 yr and ... -
Structure of an aliphatic amidase from Geobacillus pallidus RAPc8
(International Union of Crystallography, 2007)The amidase from Geobacillus pallidus RAPc8, a moderate thermophile, is a member of the nitrilase superfamily and catalyzes the conversion of amides to the corresponding carboxylic acids and ammonia. It shows both ... -
Structure of rhodolith beds from 4 to 55 meters deep along the southern coast of Espírito Santo State, Brazil
(Universidad Autónoma de Baja California, 2007)Rhodoliths are one of the most extensive benthic communities of the Brazilian continental shelf, but their structure is poorly known. The richest marine flora of Brazil’s coastal zone is found in Espírito Santo State and ... -
Students' ontological security and agency in science education - an example from reasoning about the use of gene technology
(Taylor & Francis, 2013)This paper reports on a study of how students' reasoning about socioscientific issues is framed by three dynamics: societal structures, agency and how trust and security issues are handled. Examples from gene technology ... -
Study of hydrogen storage properties of oxygen modified Ti- based AB2 type metal hydride alloy
(Elsevier, 2021)A multi component AB2 type hydrogen storage intermetallic alloy (A = Ti0.85Zr0.15, B2 = Mn1.22Ni0.22Cr0.2V0.3Fe0.06; was investigated in this work. The intermetallic specified above was modified by oxygen to yield the ... -
Sub-analysis of cyp-guides data: Assessing the prevalence and impact of drug-gene interactions in an ethnically diverse cohort of depressed individuals
(Frontiers Media, 2022)Minority groups are underrepresented in pharmacogenomics (PGx) research. Recent sub-analysis of CYP-GUIDES showed reduced length of stay (LOS) in depressed patients with CYP2D6 sub-functional status. Our primary objective ... -
Sublittoral seaweed communities on natural and artificial substrata in a high-latitude coral community in South Africa
(National Inquiry Services Centre (NISC), 2016)Coral mortality may result in macroalgal proliferation or a phase shift into an alga dominated state. Subtidal, high-latitude western Indian Ocean coral communities at Sodwana Bay on the KwaZulu-Natal coast, South Africa, ... -
Summer and winter differences in zooplankton biomass, distribution and size composition in the KwaZulu-Natal Bight, South Africa
(National Inquiry Services Centre (NISC), 2016)Zooplankton biomass and distribution in the KwaZulu-Natal Bight were investigated in relation to environmental parameters during summer (January–February 2010) and winter (July–August 2010). Mean zooplankton biomass was ... -
Superhorizon perturbations: A possible explanation of the hubble–lemaître tension and the large-scale anisotropy of the universe
(IOP Publishing, 2022)Current cosmological observations point to a serious discrepancy between the observed Hubble parameter obtained using direct versus cosmic microwave background radiation measurements. Besides this so-called Hubble– Lemaî tre ... -
Superhorizon Perturbations: A Possible Explanation of the Hubble–Lemaître Tension and the Large-scale Anisotropy of the Universe.
(The American Astronomical Society., 2022)Current cosmological observations point to a serious discrepancy between the observed Hubble parameter obtained using direct versus cosmic microwave background radiation measurements. Besides this so-called Hubble– Lemaître ... -
Supplementation of recombinant cellulases with LPMOs and CDHs improves consolidated bioprocessing of cellulose
(Elsevier, 2023)The increased demand for energy has sparked a global search for renewable energy sources that could partly replace fossil fuel resources and help mitigate climate change. Cellulosic biomass is an ideal feedstock for renewable ... -
Supported 3-D Pt nanostructures: the straightforward synthesis and enhanced electrochemical performance for methanol oxidation in an acidic medium
(Springer, 2013)Noble metal nanostructures with branched morphologies [i.e., 3-D Pt nanoflowers (NFs)] by tridimensionally integrating onto conductive carbon materials are proved to be an efficient and durable electrocatalysts for methanol ... -
A surface acoustic wave touchscreen-type device using two transducers
(2008)Current wireless human-computer interaction devices such as wireless mice and touchscreens, by and large, incorporate a sophisticated electronic architecture. The sophistication achieves wireless capabilities but carries ... -
Surface-modified polyacrylonitrile nanofibers as supports
(Springer Verlag, 2017)Polyacrylonitrile nanofibers (PAN-nfs) are one of the most studied nanofibres because of their excellent characteristics, such as good mechanical strength, chemical resistance, and good thermal stability. Due to the easy ...