Faculty of Natural Sciences: Recent submissions
Now showing items 1481-1500 of 2642
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Inhibiting CDK6 activity by quercetin is an attractive strategy for cancer therapy
(American Chemical Society, 2020)Cyclin-dependent kinase 6 (CDK6) is a potential drug target that plays an important role in the progression of different types of cancers. We performed in silico and in vitro screening of different natural compounds and ... -
The 2020 release of the ExoMol database: Molecular line lists for exoplanet and other hot atmospheres
(Elsevier, 2020)The ExoMol database (www.exomol.com) provides molecular data for spectroscopic studies of hot atmospheres. While the data are intended for studies of exoplanets and other astronomical bodies, the dataset is widely applicable. ... -
Mechanochemical synthesis and physicochemical characterization of isoniazid and pyrazinamide co-crystals with Glutaric acid
(Frontiers Media S.A., 2020)The present work reports two novel pharmaceutical co-crystals; 2:1 isoniazid-glutaric acid (INHGA) and 2:1 pyrazinamide-glutaric acid (PGA). Isoniazid and pyrazinamide are key first-line drugs used for the treatment of ... -
A preliminary study of a graphene fractal sierpinski antenna
(Institute of Physics Publishing, 2020)We provide a preliminary study of a Graphene fractal antenna operating at THz frequencies with the opportunity to modulate the emission. There are many advantages of the fractal design, namely multiband/wideband ability, ... -
Records of ctenophores from South Africa
(PeerJ, 2021)Although ctenophores can be conspicuous components of the plankton in coastal marine ecosystems, only six species have been formally described from around South Africa. Using photographs from local community scientists, ... -
Transformation of fly ash based nanosilica extract to BEA zeolite and its durability in hot liquid
(Elsevier, 2020)Power generation in South Africa relies heavily on the combustion of coal and during this process, coal fly ash (CFA) is generated as by-product, which raises several environmental issues. The transformation of CFA into a ... -
Photoluminescence quenching of a novel electroconductive poly(Propylene thiophenoimine)-co-poly(ethylenedioxy thiophene) star copolymer
(MPDI, 2020)A generation 1 poly(propylene thiophenoimine)-co-poly(ethylenedioxy thiophene) (G1PPT-co-PEDOT) star copolymer, which exhibits a strong optical absorption over a broad range in the ultraviolet–visible (UV-Vis) region and ... -
Gold nanoparticles synthesized using extracts of cyclopia intermedia, commonly known as honeybush, amplify the cytotoxic effects of doxorubicin
(MPDI, 2021)Cyclopia intermedia (C. intermedia) is an indigenous South African shrub used to prepare the popular medicinal honeybush (HB) tea. This plant contains high levels of mangiferin (MGF), a xanthonoid that was reported to have ... -
Mathematical analysis of TB model with vaccination and saturated incidence rate
(Hindawi, 2020)The model system of ordinary differential equations considers two classes of latently infected individuals, with different risk of becoming infectious. The system has positive solutions. By constructing a Lyapunov function, ... -
Groundwater prediction using machine-learning tools
(MPDI, 2020)Predicting groundwater availability is important to water sustainability and drought mitigation. Machine-learning tools have the potential to improve groundwater prediction, thus enabling resource planners to: (1) anticipate ... -
Global analysis of the COVID-19 pandemic using simple epidemiological models
(Elsevier, 2021)Several analytical models have been developed in this work to describe the evolution of fatalities arising from coronavirus COVID-19 worldwide. The Death or ‘D’ model is a simplified version of the well-known SIR ... -
The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
(Elsevier, 2021)Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility. As excess adiposity causes ... -
Encapsulation of variabilin in stearic acid solid lipid nanoparticles enhances its anticancer activity in vitro
(MDPI, 2020)The use of natural products as chemotherapeutic agents is well established; however, many of these are associated with undesirable side effects, including high toxicity and instability. Furthermore, the development of drug ... -
Silver nanoparticles stimulates spermatogenesis impairments and hematological alterations in testis and epididymis of Male rats
(MDPI, 2020)The potential pharmaceutical application of nanoparticles has led to the toxicity within the male reproductive system. In the present study, the effects of silver nanoparticles (Ag-NPs) on hematological parameters, free ... -
An insight into the mechanism of holamine- and funtumine-induced cell death in cancer cells
(MDPI, 2020)Holamine and funtumine, steroidal alkaloids with strong and diverse pharmacological activities are commonly found in the Apocynaceae family of Holarrhena. The selective anti-proliferative and cell cycle arrest effects of ... -
The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
(Elsevier, 2020)Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility. As excess adiposity causes ... -
Metal hydride hydrogen storage tank for fuel cell utility vehicles
(Elsevier, 2020)The “low-temperature” intermetallic hydrides with hydrogen storage capacities below 2 wt% can provide compact H2 storage simultaneously serving as a ballast. Thus, their low weight capacity, which is usually considered as ... -
Application of seismic stratigraphy in reservoir characterisation: A case study of the passive margin deposits of the northern Orange Basin, South Africa
(Springer Nature, 2020)The Barremian-Cenozoic depositional sequences in the northern Orange Basin, SW, South Africa, were investigated using the principles of seismic stratigraphy to understand the interplay of tectonics and sedimentary processes ... -
Maternal and Neonatal Group B Streptococcus colonisation in a cohort of Libyan women
(2021-01-18)Background: Group B streptococcus (GBS) may be vertically transmitted from mother to infant during labour and cause life threatening neonatal sepsis. The objective of this study was to determine the risk and prevalence ... -
Microalgae as a biocathode and feedstock in anode chamber for a self-sustainable microbial fuel cell technology: A review
(Elsevier, 2020)Microbial fuel cell (MFC) technology has been investigated for over a decade now and it has been deemed as a preferred technique for energy generation since it is environmentally benign and does not produce toxic by/end ...