Faculty of Natural Sciences: Recent submissions
Now showing items 161-180 of 2572
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Sub-analysis of cyp-guides data: Assessing the prevalence and impact of drug-gene interactions in an ethnically diverse cohort of depressed individuals
(Frontiers Media, 2022)Minority groups are underrepresented in pharmacogenomics (PGx) research. Recent sub-analysis of CYP-GUIDES showed reduced length of stay (LOS) in depressed patients with CYP2D6 sub-functional status. Our primary objective ... -
Characterization of inpaint residuals in interferometric measurements of the epoch of reionization
(Monthly Notices of the Royal Astronomical Society, 2023)To mitigate the effects of Radio Frequency Interference (RFI) on the data analysis pipelines of 21 cm interferometric instruments, numerous inpaint techniques have been developed. In this paper, we examine the qualitative ... -
A conceptual model for the development and management of the Cape Flats aquifer, South Africa
(Water Research Commission, 2010)This paper provides an integrated approach to the analysis of the geological, hydrological and hydrogeological characteristics of the Cape Flats: a coastal plain sand formed within the mountains of the Cape Town metropolitan ... -
On the time delay between ultra-relativistic particles
(Elsevier, 2016)The time delay between the receptions of ultra-relativistic particles emitted simultaneously is a useful observable for both fundamental physics and cosmology. The expression of the delay when the particles travel through ... -
A simple, high-throughput modeling approach reveals insights into the mechanism of gametophytic self-incompatibility
(Nature Research, 2016)Specificity in the GSI response results from the S-haplotype-specific molecular interaction of S-locus F-box (SLF/SFB) and SRNase proteins in the self-incompatibility locus (S-locus). The answer to the question of how ... -
Post-translational cleavage of recombinantly expressed nitrilase from Rhodococcus rhodochrous J1 yields a stable, active helical form
(Wiley, 2007)Nitrilases convert nitriles to the corresponding carboxylic acids and ammonia. The nitrilase from Rhodococcus rhodochrous J1 is known to be inactive as a dimer but to become active on oligomerization. The recombinant enzyme ... -
2-phenoxyethanol as anaesthetic in removing and relocating 102 species of fishes representing 30 families from sea world to uShaka Marine World, South Africa
(AOSIS, 2008)The South African Association for Marine Biological Research, incorporating Sea World, Oceanographic Research Institute and the Dolphinarium relocated from their old premises of 46 years on Durban’s beach front in March ... -
Simulating a full-sky high resolution Galactic synchrotron spectral index map using neural networks
(Monthly Notices of the Royal Astronomical Society, 2023)We present a model for the full-sky diffuse Galactic synchrotron spectral index with an appropriate level of spatial structure for a resolution of 56 arcmin (to match the resolution of the Haslam 408 MHz data). Observational ... -
Characterization and expression analysis of heme oxygenase genes from sorghum bicolor
(SAGE Publications, 2019)Heme oxygenases (HOs) have a major role in phytochrome chromophore biosynthesis, and chromophores in turn have antioxidant properties. Plant heme oxygenases are divided into the HO1 sub-family comprising HO1, HO3, and ... -
Disentangling non-gaussianity, bias, and general relativistic effects in the galaxy distribution
(American Physical Society, 2012)Local non-Gaussianity, parametrized by f NL , introduces a scale-dependent bias that is strongest at large scales, precisely where general relativistic (GR) effects also become significant. With future data, it should ... -
Computational characterization of iron metabolism in the tsetse disease vector, glossina morsitans: Ire stem-loops
(BMC, 2016)Iron metabolism and regulation is an indispensable part of species survival, most importantly for blood feeding insects. Iron regulatory proteins are central regulators of iron homeostasis, whose binding to iron response ... -
Reports of Plant-Derived Nanoparticles for Prostate Cancer Therapy
(Plants, 2023)Background: Plants have demonstrated potential in providing various types of phytomedicines with chemopreventive properties that can combat prostate cancer. However, despite their promising in vitro activity, the incorporation ... -
Synthesis of hydroxy sodalite from coal fly ash for biodiesel production from waste-derived maggot oil
(MDPI, 2019)Zeolites are aluminosilicate crystalline materials known for their unique characteristics, and have been prominent for nearly half a century due to their wide and important industrial applications. The production of zeolites, ... -
The validation of a simple, robust, stability-indicating rp-hplc method for the simultaneous detection of lamivudine, tenofovir disoproxil fumarate, and dolutegravir sodium in bulk material and pharmaceutical formulations
(Hindawi, 2022)An effective analytical method is requisite to ensure the accurate identification and quantification of drug(s), either in bulk material or in complex matrices, which form part of finished pharmaceutical products. For the ... -
Ozone and nitric oxide induce cGMP-dependent and independent transcription of defence genes in tobacco
(Wiley, 2009)Here, we analyse the temporal signatures of ozone (O3)-induced hydrogen peroxide (H2O2) and nitric oxide (NO) and the role of the second messenger guanosine 3′,5′-cyclic monophosphate (cGMP) in transcriptional changes ... -
Identification of a novel alkaliphilic esterase active at low temperatures by screening a metagenomic library from Antarctic desert soil
(American Society for Microbiology, 2009)The cold deserts of the McMurdo Dry Valleys, South Victoria Land, Eastern Antarctica, are widely acknowledged as having the harshest soil environments on Earth (6, 8, 26). Despite the apparent hostility of the environment, ... -
Fabrication of polyoxometalate-modified palladium–nickel/reduced graphene oxide alloy catalysts for enhanced oxygen reduction reaction activity
(Royal Society of Chemistry, 2021)Designing advanced nanocatalysts for effectively catalyzing the oxygen reduction reaction (ORR) is of great importance for practical applications of direct methanol fuel cells (DMFCs). In this work, the reduced graphene ... -
Binary codes from m-ary n-cubes Q(n) (m)
(American Institute of Mathematical Sciences, 2021)We examine the binary codes from adjacency matrices of the graph with vertices the nodes of the m-ary n-cube Qmn and with adjacency de ned by the Lee metric. For n = 2 and m odd, we obtain the parameters of the code and ... -
Situation analysis on the regulation of nanomedicines in Southern Africa
(Frontiers Media, 2023)Medical products incorporating nanoparticle drug delivery systems (nanomedicines) are therapeutic or imaging agents, which comprise a delivery system within the nanometer size range (1 – 1000 nm). As medical products, ... -
Wide-angle effects in multi-tracer power spectra with Doppler corrections
(IOP Publishing, 2023). We examine the computation of wide-angle corrections to the galaxy power spectrum including redshift-space distortions and relativistic Doppler corrections, and also including multiple tracers with differing clustering, ...