Browsing Research Publications by Title
Now showing items 363-382 of 802
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In silico inhibition of SGTP4 as a therapeutic target for the treatment of schistosomiasis
(Taylor and Francis Group, 2020) -
In utero art exposure and birth and early growth outcomes among HIV-exposed uninfected infants attending immunization services: Results from national pmtct surveillance, South Africa
(Oxford University Press, 2017). Despite the recognized benefit of antiretroviral therapy (ART) for preventing and treating HIV, some studies have reported adverse birth outcomes with in utero ART exposure. We evaluated the effect of infant in utero ... -
An in vitro study on the combination effect of metformin and N-Acetyl cysteine against hyperglycaemia-Induced cardiac damage
(MDPI, 2019-11-21)Chronic hyperglycaemia is a major risk factor for diabetes-induced cardiovascular dysfunction. In a hyperglycaemic state, excess production of reactive oxygen species (ROS), coupled with decreased levels of glutathione, ... -
Increasing resilience to the SARS-CoV-2 virus and other health threats in food-insecure communities
(MedPharm Publications, 2021)The health of the majority of South Africa’s population is seriously threatened by hunger and micronutrient deficiency, with impaired immune response a real threat, which the current SARSCoV-2 virus pandemic has highlighted. ... -
Independent and interactive effects of HIV infection, clinical stage and other comorbidities on survival of children treated for severe malnutrition in rural South Africa: A retrospective multicohort study
(Health & Medical Publishing Group, 2017)BACKGROUND. There is still limited to no evidence on the independent and interactive effects of HIV infection, disease stage, baseline disease severity and other important comorbidities on mortality risk among young ... -
Individual and area-level socioeconomic correlates of hypertension prevalence, awareness, treatment, and control in uMgungundlovu, KwaZulu-Natal, South Africa
(BMC, 2023)Hypertension is the second leading risk factor for death in South Africa, and rates have steadily increased since the end of Apartheid. Research on the determinants of hypertension in South Africa has received considerable ... -
Inefficient procurement processes undermine access to medicines in the Western Cape Province of South Africa
(Health and Medical Publishing Group (HMPG), 2017)BACKGROUND. South Africa (SA) has experienced several stock-outs of life-saving medicines for the treatment of major chronic infectious and non-communicable diseases in the public sector. OBJECTIVE. To identify the causes ... -
Inequity in the distribution of non-communicable disease multimorbidity in adults in South Africa: An analysis of prevalence and patterns
(Frontiers Media, 2022)The present study examined the prevalence and patterns of noncommunicable disease multimorbidity by wealth quintile among adults in South Africa. The South African National Income Dynamics Study Wave 5 was conducted ... -
INFORMAS (International Network for Food and Obesity/non-communicable diseases Research, Monitoring and Action Support): overview and key principles
(John Wiley & Sons, 2013)Non-communicable diseases (NCDs) dominate disease burdens globally and poor nutrition increasingly contributes to this global burden. Comprehensive monitoring of food environments, and evaluation of the impact of public ... -
Information for human resource management
(Health Systems Trust, 2005)This chapter emphasises the need for a routine information system for Human Resources Management (HRM). It provides an assessment of the current information system for HRM using a case study approach. It also outlines a ... -
Infrastructure, policy and regulatory interventions to increase physical activity to prevent cardiovascular diseases and diabetes: A systematic review
(BMC, 2023)Noncommunicable diseases are major contributors to morbidity and mortality worldwide. Modifying the risk factors for these conditions, such as physical inactivity, is thus essential. Addressing the context or circum‑ stances ... -
Innovative, rapid, high-throughput method for drug repurposing in a pandemic—A case study of SARS-CoV-2 and Covid-19
(Frontiers Media, 2023)Several efforts to repurpose drugs for COVID-19 treatment have largely either failed to identify a suitable agent or agents identified did not translate to clinical use. Reasons that have been suggested to explain the ... -
Integrated community case management of childhood illness in low- and middle-income countries
(John Wiley and Sons Ltd, 2021)The leading causes of mortality globally in children younger than five years of age (under-fives), and particularly in the regions of sub-Saharan Africa (SSA) and Southern Asia, in 2018 were infectious diseases, including ... -
Integrated knowledge translation to advance noncommunicable disease policy and practice in South Africa: Application of the exploration, preparation, implementation, and sustainment (epis) framework
(BMC, 2021)In response to the “know–do” gap, several initiatives have been implemented to enhance evidenceinformed decision-making (EIDM). These include individual training, organizational culture change management, and legislative ... -
Integrated management of Type 2 diabetes and Gestational diabetes in the context of multi-morbidity in Africa: A systematic review
(Ubiquity Press, 2022)Many adults diagnosed with gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) also have other known or unknown comorbid conditions. The rising prevalence of GDM and T2DM within a broader context ... -
Integrating community health assistant- driven sexual and reproductive health services in the community health system in Nyimba district in Zambia: Mapping key actors, points of integration, and conditions shaping the process
(Reproductive Health, 2019)Introduction: Although large scale public sector community health worker programs have been key in providing sexual and reproductive health (SRH) services in low- and middle-income countries, their integration process into ... -
Integrating community health assistant-driven sexual and reproductive health services in the community health system in Nyimba district in Zambia: Mapping key actors, points of integration, and conditions shaping the process
(Reproductive Health, 2019)Introduction: Although large scale public sector community health worker programs have been key in providing sexual and reproductive health (SRH) services in low- A nd middle-income countries, their integration process ... -
Integrating gestational diabetes screening and care and Type 2 diabetes mellitus prevention after GDM into community based primary health care in South Africa- mixed method study
(Ubiquity Press, 2022)Despite high gestational diabetes mellitus (GDM) prevalence in South Africa (9.1% in 2018), its screening and management are not well integrated into routine primary health care and poorly linked to post-GDM prevention ... -
Integrating health technology assessment and the right to health in South Africa: a qualitative content analysis of substantive values in landmark judicial decisions
(Cambridge University Press, 2023)The World Health Assembly has encouraged WHO member-states to establish capacity in health technology assessment (HTA) as a support for achieving universal health coverage (UHC). Simultaneously, the WHO has stated that UHC ... -
Integrating the prevention of mother-to-child transmission of HIV into primary healthcare services after AIDS denialism in South Africa: perspectives of experts and health care workers - a qualitative study
(Springer Nature, 2020)Integrating Prevention of Mother-to-Child Transmission (PMTCT) programmes into routine health services under complex socio-political and health system conditions is a priority and a challenge. The successful rollout of ...