Library Portal | UWC Portal | National ETDs | Global ETDs
    • Login
    Contact Us | About Us | FAQs | Login
    View Item 
    •   DSpace Home
    • Faculty of Natural Sciences
    • South African Herbal Science and Medicine Institute (SAHSMI)
    • Research Articles (SAHSMI)
    • View Item
    •   DSpace Home
    • Faculty of Natural Sciences
    • South African Herbal Science and Medicine Institute (SAHSMI)
    • Research Articles (SAHSMI)
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Phytochemical screening and biological activity studies of five South African indigenous medicinal plants

    Thumbnail
    View/Open
    Babajide_Phytochemical screening_2010.pdf (197.3Kb)
    Date
    2010
    Author
    Babajide, Jelili Olalekan
    Mabusela, Wilfred T.
    Green, Ivan
    Ameer, Farouk
    Weitz, Frans
    Iwuoha, Emmanuel I.
    Metadata
    Show full item record
    Abstract
    Different extracts and fractions of five selected indigenous South African medicinal plants, namely, Cissampelos capensis, Geranium incanum and three Gethyllis species, were subjected to phytochemical screening and testing for cytotoxicity using the brine shrimp lethality bioassay, and antimicrobial activity assays against nine microbes, which included three fungal species, three Gram negative and three Gram positive bacteria.The majority of the extracts tested positive for the presence of tannins, phenolics and flavonoids, while in selected cases, phytochemical tests suggested the presence of essential oils, glycosides or alkaloids. The methanol extract of Gethyllis gregoriana displayed the highest cytotoxicity levels. Generally, the highest levels of biological activity were shown to reside in the methanolic extracts, while hexane extracts revealed very low to zero activity. The total tertiary alkaloid (TTA) of C. capensis was mostly active against Bacillus subtilis, a Gram +ve bacteria. The trends observed for the cytotoxicity assay were in agreement with those observed for the antimicrobial assay.
    URI
    http://hdl.handle.net/10566/2296
    Collections
    • Research Articles (SAHSMI)

    DSpace 6.3 | Ubuntu | Copyright © University of the Western Cape
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Browse

    All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    Login

    Statistics

    View Usage Statistics

    DSpace 6.3 | Ubuntu | Copyright © University of the Western Cape
    Contact Us | Send Feedback
    Theme by 
    Atmire NV