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    Antimicrobial activities of a novel biflavonoid and other constituents from Rhus natalensis

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    Mwangi_Antimicrobial_2013.pdf (295.9Kb)
    Date
    2013
    Author
    Mwangi, Henry M.
    Mabusela, Wilfred T.
    Abegaz, Berhanu M.
    Martin, Onani O.
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    Abstract
    Phytochemical studies on Rhus natalensis root bark collected from Kenya led to the isolation and identification of a new biflavonoid (3-(1-(2,4-dihydroxyphenyl)-3,3-bis(4-hydroxyphenyl)-1-oxopropan-2- yl)-7-methoxy-4H-chromone-4-one (1), named rhuschromone, in addition to two other known compounds; 2',4'-dihydroxychalcone-(4-O-5''')-4'',2''',4'''-trihydroxychalcone (2) and 3-((Z)-heptadec-13- enyl) benzene-1,2-diol (3). The chemical structures of the isolated compounds were established using spectroscopic techniques including high field nuclear magnetic resonance (NMR). The total extracts and the isolated compounds were tested for their antimicrobial activities against different strains of bacteria.
    URI
    http://hdl.handle.net/10566/2298
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    • Prof. Martin O Onani (Chemistry)
    • Research Articles (SAHSMI)

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