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Comparative evaluation of pharmacy students’ knowledge and skills in maternal and child health: Traditional versus integrated curriculum
(MDPI, 2022): Reducing maternal and child mortality is a health priority in South Africa. Therefore, health professional education should produce graduates that can meet these needs. This study compared the maternal and child health ... -
Establishing a pharmacist–prescriber partnership in publicly funded primary healthcare clinics to optimise antibiotic prescribing in the Western Cape: An exploratory study
(AOSIS, 2020)Promoting evidence-based antibiotic prescribing through successful antimicrobial stewardship (AMS) programmes is critical to preserving the effectiveness of antibiotics for common infections in primary care. This requires ... -
Continuous professional development for public sector pharmacists in South Africa: A case study of mapping competencies in a pharmacists’ preceptor programme
(MPDI, 2020)Lifelong learning among healthcare practitioners is crucial to keep abreast of advances in therapeutic and service delivery approaches. In South Africa, continuous professional development (CPD) was mandated (2019) for ... -
Pharmacists’ approach to optimise safe medication use in paediatric patients
(MPDI, 2021)Paediatric patients are unique, yet challenging patients to care for by pharmacists. Paediatric medicine use requires special consideration. Pharmacists play an important role in educating and counselling patients, carers, ... -
Medicines regulatory science expertise in Africa: workforce capacity development and harmonisation activities towards the establishment of the African medicines agency
(Adis, 2022)The medicines regulatory landscape in Africa is undergoing transformation with at least two countries having National Medicines Regulatory Authorities (NRAs) that operate at World Health Organization (WHO) maturity level ... -
Parental reporting of adverse drug reactions in South Africa: An online survey
(AOSIS, 2021)The high incidence of adverse drug reactions (ADRs) in children is of global concern. Enhancing the reporting of ADRs could contribute to making safer medicines available to children.To assess parents’ awareness of ... -
Venous thromboembolism risk assessment and prophylaxis in hospitalised medical patients in the Cape Town metropole, South Africa
(South African Medical Association, 2022)Venous thromboembolism (VTE) is regarded as the most preventable cause of inpatient death in hospital settings globally. VTE can be prevented through the provision of non-pharmacological and/or pharmacological thromboprophylaxis ... -
Meningitis during COVID -19 pandemic in the Democratic Republic of Congo: A call for concern
(Elsevier, 2022-01-01)Meningitis is a severe infection and a significant public health challenge. The meningitis outbreak resurfaced amid the coronavirus disease 2019 (COVID-19) pandemic in the Democratic Republic of Congo (DRC). The outbreak ... -
Marburg virus disease outbreak amidst COVID-19 in the Republic of Guinea: A point of contention for the fragile health system?
(Elsevier, 2022)In August 2021, the Marburg virus disease (MVD) outbreak was confirmed amid the coronavirus disease 2019 (COVID-19) pandemic in the Republic of Guinea. This is the first time it is detected in Guinea and West Africa. Marburg ... -
Common defciencies found in generic Finished Pharmaceutical Product (FPP) applications submitted for registration to the South African Health Products Regulatory Authority (SAHPRA)
(Springer Nature, 2022)The aim of the study was to investigate the common defciencies observed in the Finished Pharmaceutical Product (FPP) section of generic product applications submitted to SAHPRA. The study was conducted retrospectively ... -
Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer’s disease agents
(Taylor & Francis Open Access, 2021)Multitarget directed ligands (MTDLs) are emerging as promising treatment options for Alzheimer’s disease (AD). Coumarin derivatives serve as a good starting point for designing MTDLs due to their inherent inhibition of ... -
Development and implementation of an integrated framework for undergraduate pharmacy training in maternal and child health at a South African university
(MPDI, 2021)The South African Pharmacy Council (SAPC) regulates undergraduate pharmacy education and pharmacy practice. The SAPC Good Pharmacy Practice manual describes the role of pharmacists in maternal and child health (MCH) in ... -
Discovery of 9-phenylacridinediones as highly selective butyrylcholinesterase inhibitors through structure-based virtual screening
(Elsevier, 2020)Butyrylcholinesterase (BuChE) is considered a promising drug target as it plays an important role in the pro-gression of late stage Alzheimer’s disease (AD). Two compound libraries were selected and 64 124 aminecontaining ... -
Cheminformatic profiling and hit prioritization of natural products with activities against Methicillin-Resistant Staphylococcus Aureus (MRSA)
(MPDI, 2021)Several natural products (NPs) have displayed varying in vitro activities against methicillinresistant Staphylococcus aureus (MRSA). However, few of these compounds have not been developed into potential antimicrobial ... -
Service learning in pharmacy: Implementation of tuberculosisscreening by second-year pharmacy studentsin primary health care facilitiesin Cape Town, South Africa
(FIP, 2021)The School of Pharmacy of the University of the Western Cape implemented a service learning programme where second year students participated in tuberculosis (TB) screening.To determine the views of students and nurses about ... -
Structural Insights and Docking Analysis of Adamantane-Linked 1,2,4-Triazole Derivatives as Potential 11 -HSD1 Inhibitors
(Molecules, 2021)The solid-state structural analysis and docking studies of three adamantane-linked 1,2,4- triazole derivatives are presented. Crystal structure analyses revealed that compound 2 crystallizes in the triclinic P-1 space ... -
Computational applications in secondary metabolite discovery (caismd): An online workshop
(BMC, 2021)We report the major conclusions of the online open-access workshop “Computational Applications in Secondary Metabolite Discovery (CAiSMD)” that took place from 08 to 10 March 2021. Invited speakers from academia and industry ... -
Preceptor reflections on the Community Health clinical rotation for fourth year pharmacy students at the University of the Western Cape
(2019)This paper describes the community health clinic rotation of the Patient Care Experience programme (PaCE) offered to fourth year pharmacy students (2018) at the University of the Western Cape. Reflections from the collective ... -
Alternative mechanisms for delivery of medication in South Africa: A scoping review
(AOSIS, 2021)Background: The number of people in South Africa with chronic conditions is a challenge to the health system. In response to the coronavirus infection, health services in Cape Town introduced home delivery of medication ... -
Cheminformatic Profiling and Hit Prioritization of Natural Products with Activities against Methicillin-Resistant Staphylococcus aureus (MRSA)
(Molecules, 2021-06)Several natural products (NPs) have displayed varying in vitro activities against methicillin-resistant Staphylococcus aureus (MRSA). However, few of these compounds have not been developed into potential antimicrobial ...
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