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    Task-sharing of psychological treatment for antenatal depression in Khayelitsha, South Africa: Effects on antenatal and postnatal outcomes in an individual randomised controlled trial

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    Date
    2020
    Author
    Lund, Crick
    Schneider, Marguerite
    Garman, Emily C
    Davies, Thandi
    Munodawafa, Memory
    Honikman, Simone
    Bhana, Arvin
    Bassf, Judith
    Bolton, Paul
    Dewey, Michael
    Joska, John
    Kagee, Ashraf
    Myer, Landon
    Petersen, Inge
    Prince, Martin
    Stein, Dan J
    Tabana, Hanani
    Thornicroft, Graham
    Tomlinson, Mark
    Hanlon, Charlotte
    Alem, Atalay
    Susser, Ezra
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    Abstract
    The study's objective was to determine the effectiveness of a task-sharing psychological treatment for perinatal depression using non-specialist community health workers. A double-blind individual randomised controlled trial was conducted in two antenatal clinics in the peri-urban settlement of Khayelitsha, Cape Town. Adult pregnant women who scored 13 or above on the Edinburgh Postnatal Depression rating Scale (EPDS) were randomised into the intervention arm (structured six-session psychological treatment) or the control arm (routine antenatal health care and three monthly phone calls). The primary outcome was response on the Hamilton Depression Rating Scale (HDRS) at three months postpartum (minimum 40% score reduction from baseline) among participants who did not experience pregnancy or infant loss (modified intention-to-treat population) (registered on Clinical Trials: NCT01977326).
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    http://hdl.handle.net/10566/5274
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