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The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
(BioMed Central, 2018)
BACKGROUND: Cytokines and hormones, including insulin, are known to modulate the hypothalamic-pituitary-testes
axis and steroidogenesis, both centrally and peripherally. In the context of chronic inflammation and
hyper ...
Effect of the metabolic syndrome on male reproductive function: a case-controlled pilot study
(Wiley, 2014)
The metabolic syndrome (MetS) is a constellation of various risk factors. This
study aimed to investigate the effect of MetS on testosterone and progesterone,
and semen parameters, in a case-controlled pilot study. Male ...
Obesity is associated with increased seminal insulin and leptin alongside reduced fertility parameters in a controlled male cohort
(BioMed Central, 2014)
Obesity appears to be associated with male reproductive dysfunction and infertility, although this has been inconsistent and inconclusive. Insulin and leptin are known mediators and modulators of the hypothalamus-pituitary-testes ...
The impact of male overweight on semen quality and outcome of assisted reproduction
(Medknow Publications, 2014)
The impact of obesity on male reproductive health remains a
contested topic as evidence is inconclusive and inconsistent. Even
more debatable is the effect of male obesity in assisted reproduction.
In the manuscript, ...