Associations of unprocessed and processed meat intake with mortality and cardiovascular disease in 21 countries [Prospective Urban Rural Epidemiology (PURE) Study]: A prospective cohort study
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Date
2021Author
Iqbal, Romaina
Dehghan, Mahshid
Tsolekile, Lungi
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Show full item recordAbstract
Dietary guidelines recommend limiting red meat
intake because it is a major source of medium- and long-chain SFAs
and is presumed to increase the risk of cardiovascular disease (CVD).
Evidence of an association between unprocessed red meat intake and
CVD is inconsistent. The study aimed to assess the association of unprocessed
red meat, poultry, and processed meat intake with mortality and
major CVD. The Prospective Urban Rural Epidemiology (PURE)
Study is a cohort of 134,297 individuals enrolled from 21 low-,
middle-, and high-income countries. Food intake was recorded using
country-specific validated FFQs. The primary outcomes were total
mortality and major CVD. HRs were estimated using multivariable
Cox frailty models with random intercepts.