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Capacity building for whole genome sequencing of Mycobacterium tuberculosis and bioinformatics in high TB burden countries
(Oxford University Press, 2020)
Background
Whole-genome sequencing (WGS) is increasingly used for Mycobacterium tuberculosis (Mtb) research. Countries with the highest tuberculosis (TB) burden face important challenges to integrate WGS into surveillance ...
The combat-tb workbench: Making powerful Mycobacterium tuberculosis bioinformatics accessible
(American Society for Microbiology, 2022)
Whole-genome sequencing (WGS) is a powerful method for detecting drug resistance, genetic diversity, and transmission dynamics of Mycobacterium tuberculosis. Implementation of WGS in public health microbiology laboratories ...
Repurposing based identification of novel inhibitors against mmps5-mmpl5 efflux pump of Mycobacterium smegmatis: A combined in silico and in vitro study
(MDPI, 2022)
In the current era of a pandemic, infections of COVID-19 and Tuberculosis (TB) enhance
the detrimental effects of both diseases in suffering individuals. The resistance mechanisms evolving
in Mycobacterium tuberculosis ...