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DDEC: Dragon databaseof genes implicated in esophageal cancer
(BioMed Central, 2009)
Esophageal cancer ranks eighth in order of cancer occurrence. Its lethality primarily stems from inability to detect the disease during the early organ-confined stage and the lack of effective therapies for advanced-stage ...
Evaluation of protein purification techniques and effects of storage duration on lc-ms/ms analysis of archived ffpe human crc tissues
(Frontiers Media, 2021)
To elucidate cancer pathogenesis and its mechanisms at the molecular level, the collecting
and characterization of large individual patient tissue cohorts are required. Since most
pathology institutes routinely preserve ...
Structural and molecular docking analytical studies of the predicted ligand binding sites of cadherin-1 in cancer prognostics
(Dove Medical Press, 2020)
Several studies have explored the design of antimicrobial peptides (AMPs) for the
development of therapeutic and diagnostic molecules for the treatment and identification of
pathogenic diseases as well as cancer. Human ...
Modelling human protein interaction networks as metric spaces has potential in disease research and drug target discovery
(BMC, 2014)
We have recently shown by formally modelling human protein interaction networks (PINs) as metric
spaces and classified proteins into zones based on their distance from the topological centre that hub proteins are
primarily ...
Investigation of distinct gene expression profile patterns that can improve the classification of intermediate-risk prognosis in AML patients
(Frontiers Media, 2023)
Acute myeloid leukemia (AML) is a heterogeneous type of blood cancer that generally affects the elderly. AML patients are categorized with favorable-, intermediate-, and adverse-risks based on an individual’s genomic ...
Transforming RNA-Seq gene expression to track cancer progression in the multi-stage early to advanced-stage cancer development
(Public Library of Science, 2023)
Cancer progression can be tracked by gene expression changes that occur throughout early-stage to advanced-stage cancer development. The accumulated genetic changes can be detected when gene expression levels in advanced-stage ...