Modeling the dynamics of an epidemic under vaccination in two interacting populations

Abstract

Mathematical modeling of the numerical evolution of infectious diseases has become an important tool for disease control and eradication when possible. Much work has been done on the problem of how a given population is affected by another population when there is mutual interaction. The mere presence of migrant people poses a challenge to whatever health systems are in place in a particular region. Such epidemiological phenomena have been studied extensively, described by mathematical models with suggestions for intervention strategies. The epidemiological effect of migration within the population itself was modeled for sleeping sickness in a paper 1 by Chalvet-Monfray et al. In the case of malaria, there is for instance a study 2 by Tumwiine et al. on the effect of migrating people on a fixed population. The latter two diseases are vector borne. Diseases that propagate without a vector spread perhaps more easily when introduced into a new region. Various studies of models with immigration of infectives have been undertaken for tuberculosis, see for instance 3 by Zhou et al., or the work 4 of Jia et al., and for HIV, see the paper 5 of Naresh et al.