Browsing Faculty of Natural Sciences by Title
Now showing items 534-553 of 2571
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The design and evaluation of ciprofloxacin-loaded nanoformulations using Ipomoea batatas starch nanoparticles
(SpringerOpen, 2023)Starch nanoparticle derivatives are gaining popularity as drug delivery vehicles because of their biocompatibility, better mechanical characteristics, heat stability properties, impediment qualities, permeability ... -
Design and synthesis of acyldepsipeptide-1 analogues: antibacterial activity and cytotoxicity screening
(Arabian Journal of Chemistry, 2023)Acyldepsipeptides (ADEPs) are receiving more attention as prospective antimicrobial agents due to their unique mode of action and chemical properties. However, their therapeutic potential is limited by their poor pharmacokinetic ... -
Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer’s disease agents
(Taylor & Francis Open Access, 2021)Multitarget directed ligands (MTDLs) are emerging as promising treatment options for Alzheimer’s disease (AD). Coumarin derivatives serve as a good starting point for designing MTDLs due to their inherent inhibition of ... -
A designed experiments approach to optimizing MALDI-TOF MS spectrum processing parameters enhances detection of antibiotic resistance in Campylobacter jejuni
(Frontiers Media, 2016)MALDI-TOF MS has been utilized as a reliable and rapid tool for microbial fingerprinting at the genus and species levels. Recently, there has been keen interest in using MALDI-TOF MS beyond the genus and species levels to ... -
Designing a course model for distance-based online bioinformatics training in Africa: the H3ABioNet experience
(Public Library of Science, 2017)Africa is not unique in its need for basic bioinformatics training for individuals from a diverse range of academic backgrounds. However, particular logistical challenges in Africa, most notably access to bioinformatics ... -
Designing an optimal LSST deep drilling program for cosmology with type Ia supernovae
(American Astronomical Society, 2023)The Vera C. Rubin Observatory’s Legacy Survey of Space and Time (LSST) is forecast to collect a large sample of Type Ia supernovae (SNe Ia) expected to be instrumental in unveiling the nature of dark energy. The feat, ... -
Designing mobile phone interfaces for age diversity in South Africa: “One-World” versus diverse “Islands”
(Springer, 2013)Designing for diversity is a laudable aim. How to achieve this, in the context of mobile phone usage by South African seniors, is a moot point. We considered this question from two possible perspectives: universal ... -
Designing novel possible kinase inhibitor derivatives as therapeutics against Mycobacterium tuberculosis: An in silico study
(Scientific Reports, 2019)Rv2984 is one of the polyphosphate kinases present in Mycobacterium tuberculosis involved in the catalytic synthesis of inorganic polyphosphate, which plays an essential role in bacterial virulence and drug resistance. ... -
The detailed forms of the LMC Cepheid PL and PLC relations
(Oxford University Press, 2007)Possible deviations from linearity of the Large Magellanic Cloud Cepheid period–luminosity (PL) and period–luminosity–colour (PLC) relations are investigated. Two data sets are studied, respectively from the Optical ... -
Detecting marine heatwaves with sub-optimal data
(Frontiers, 2019)Marine heatwaves (MHWs), or prolonged periods of anomalously warm sea water temperature, have been increasing in duration and intensity globally for decades. However, there are many coastal, oceanic, polar, and sub-surface ... -
Detecting the relativistic galaxy bispectrum
(IOP Publishing Ltd, 2020)The Fourier galaxy bispectrum is complex, with the imaginary part arising from leading-order relativistic corrections, due to Doppler, gravitational redshift and related lineof-sight effects in redshift space. The detection ... -
Detection of an increasing orbital period in the subdwarf B eclipsing system NSVS 14256825
(Oxford University Press, 2012)New timings of eclipses made in 2010 and 2011 are presented for the hot subdwarf B (sdB) eclipsing binary NSVS 14256825. Composed of an sdB star and a much cooler companion, with a period near 0.1104 days, this system ... -
Detection of Cross-Correlation between Gravitational Lensing and γ Rays
(American Physical Society, 2020)In recent years, many γ -ray sources have been identified, yet the unresolved component hosts valuable information on the faintest emission. In order to extract it, a cross-correlation with gravitational tracers of ... -
A detection threshold in the amplitude spectra calculated from Kepler data obtained during K2 mission.
(Oxford University Press, 2015)We present our analysis of simulated data in order to derive a detection threshold which can be used in the pre-whitening process of amplitude spectra. In case of ground-based data of pulsating stars, this threshold is ... -
Determinants of women’s preferred and actual abortion provision locations in Nigeri
(Springer, 2021)Background: Unsafe abortion remains a leading cause of maternal mortality globally. Many factors can infuence women’s decisions around where to seek abortion care; however, little research has been done on abortion care ... -
Determination of anthracene on Ag-Au alloy nanoparticles/overoxidized-polypyrrole composite modified glassy carbon electrodes
(MDPI, 2010)A novel electrochemical sensor for the detection of anthracene was prepared by modifying a glassy carbon electrode (GCE) with over-oxidized polypyrrole (PPyox) and Ag-Au (1:3) bimetallic nanoparticles (Ag-AuNPs). The ... -
Determination of kanamycin plasma levels using LC-MS and its pharmacokinetics in patients with multidrug-resistant tuberculosis with and without HIV-infection
(OMICS, 2015)The objectives of the study were: (1) to determine kanamycin plasma concentrations using liquid chromatography coupled with mass spectrometry (LC-MS), (2) to investigate kanamycin pharmacokinetics (PK) in patients with ... -
Determination of paracetamol on electrochemically reduced graphene oxide–antimony nanocomposite modified pencil graphite electrode using adsorptive stripping differential pulse voltammetry
(MDPI, 2022)A simple, highly sensitive, accurate, and low-cost electrochemical sensor was developed for the determination of over-the-counter painkiller, paracetamol (PC). The enhanced sensing capabilities of the developed sensor ... -
Determination of reservoir flow units from core data: A case study of the lower cretaceous sandstone reservoirs, Western Bredasdorp basin offshore in South Africa
(Springer Nature, 2021)The overarching aim of this study is to use core measurements of porosity and permeability in three wells (MO1, MO2, and MO3) to generate a scheme of sandstone reservoir zonation for identification of flow units in the E-M ...