Browsing Faculty of Natural Sciences by Title
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Improving productivity and soil fertility in Medicago sativa and Hordeum marinum through intercropping under saline conditions
(BioMed Central Ltd, 2024)Background and aims: Intercropping is an agriculture system used to enhance the efficiency of resource utilization and maximize crop yield grown under environmental stress such as salinity. Nevertheless, the impact of ... -
Improving quality-of-service in cloud/fog computing through efficient resource allocation
(MPDI, 2019)Recently, a massive migration of enterprise applications to the cloud has been recorded in the IT world. One of the challenges of cloud computing is Quality-of-Service management, which includes the adoption of appropriate ... -
Improving the functionality of surface-engineered yeast cells by altering the cell wall morphology of the host strain
(Springer, 2021)The expression of functional proteins on the cell surface using glycosylphosphatidylinositol (GPI)-anchoring technology is a promising approach for constructing yeast cells with special functions. The functionality of ... -
Improving usability and correctness of a mobile tool to help a Deaf person with pharmaceutical instruction
(ACM, 2013)The computing for development community knows how to build user interfaces using qualitative methods for text il- literate users, especially on mobile devices. However, lit- tle work has been done speci cally targeting ... -
In a rough spot: Declines in Arthroleptella rugosa calling densities are explained by invasive pine trees
(Wiley, 2023)Basing conservation interventions on evidence is important for justifying their associated cost and gauging their effectiveness. For amphibians, the number of studies available to support conservation ... -
In quest of contact: phylogeography of helmeted terrapins (Pelomedusa galeata, P. subrufa sensu stricto)
(PeerJ, 2018)Based on rangewide sampling and three mitochondrial and two nuclear markers (together up to 1,850 bp and 1,840 bp, respectively), we examine the phylogeography of two helmeted terrapin species (Pelomedusa galeata and P. ... -
In silico analysis of a putative dehalogenase from the genome of halophilic bacterium Halomonas smyrnensis AAD6T
(Taylor and Francis, 2022)Microbial-assisted removal of natural or synthetic pollutants is the prevailing green, low-cost technology to treat polluted environments. However, the challenge with enzyme-assisted bioremediation is the laborious nature ... -
In Silico and In Vitro Screening of 50 Curcumin Compounds as EGFR and NF-κB Inhibitors
(MDPI, 2022)The improvement of cancer chemotherapy remains a major challenge, and thus new drugs are urgently required to develop new treatment regimes. Curcumin, a polyphenolic antioxidant derived from the rhizome of turmeric ... -
In silico identification of micrornas as candidate Colorectal cancer biomarkers
(Sage Journals, 2019)The involvement of microRNA in cancers plays a significant role in their pathogenesis. Specific expressions of these non-coding RNAs also serve as biomarkers for early colorectal cancer diagnosis, but their laboratory/molecular ... -
In silico prediction of new antimicrobial peptides and proteins as druggable targets towards alternative anti-schistosomal therapy
(Elsevier, 2021)Schistosomiasis is a debilitating disease caused by a parasitic flatworm found in fresh- water. With the exponential increase in prevalence, Praziquantel (PZQ) remains the only effective treatment drug, however, resistance ... -
In silico repurposing of a Novobiocin derivative for activity against latency associated Mycobacterium tuberculosis drug target nicotinate-nucleotide adenylyl transferase (Rv2421c)
(Public Library of Science, 2021)Nicotinamide-nucleotide adenylyl transferase (Rv2421c) was selected as a potential drug target, because it has been shown, in vitro, to be essential for Mycobacterium tuberculosis growth. It is conserved between mycobacterium ... -
In Silico Sperm Proteome Analysis to Investigate DNA Repair Mechanisms in Varicocele Patients
(Frontiers Media S.A., 2021-12-17)Varicocele, a condition associated with increased oxidative stress, negatively affects sperm DNA integrity and reduces pregnancy rates. However, the molecular mechanisms related to DNA integrity, damage, and repair in ... -
In vitro acetylcholinesterase inhibitory activity and chemical composition of the dichloromethane extracts of the leaves and inflorescences of the tumbleweed, Trachyandra laxa (N.E.Br.) Oberm. var. rigida (Suesseng.) Roessl
(South African Journal of Botany, 2022)Trachyandra laxa, which belongs to the family Asphodelaceae, is a poisonous geophyte, often consumed by livestock, particularly when pastures are poor. Ingestion of T. laxa by livestock causes paresis and paralysis of the ... -
In vitro Antidiabetic and Antioxidant effects of different extracts of Catharanthus roseus and its indole alkaloid, vindoline
(MPDI, 2020)The Catharanthus roseus plant has been used traditionally to treat diabetes mellitus. Scientific evidence supporting the antidiabetic effects of this plant’s active ingredient-vindoline has not been fully evaluated. In ... -
In vitro antioxidant mechanism of action of hibiscus sabdariffa in the induction of apoptosis against breast cancer
(Taylor and Francis Ltd., 2023)The antioxidant mechanism of action in the process of cytotoxicity, and pro-apoptotic activity of Hibiscus sabdariffa water extract (HSWE) was assessed against non-cancerous (MCF12A) and breast cancer (MCF7) cells grown ... -
In vitro comparison of the anti-proliferative effects of galenia africana on human skin cell lines
(MDPI, 2021)Malignant melanoma is the major cause of skin cancer-related deaths. Surgery in combina-tion with radiotherapy, immunotherapy or chemotherapy is used to eradicate cancer cells, however, this treatment option is limited by ... -
In vitro corrosion of titanium nitride and oxynitride-based biocompatible coatings deposited on stainless steel
(MPDI, 2020)The reactive cathodic arc deposition technique was used to produce Ti nitride and oxynitride coatings on 304 stainless steel substrates (SS). Both mono (SS/TiN, SS/TiNO) and bilayer coatings (SS/TiN/TiNO and SS/TiNO/TiN) ... -
In vitro effects of aqueous extract of unfermented rooibos on human spermatozoa
(Wiley, 2022)The inability to conceive is a baleful experience for thousands of couples worldwide. Among different well-known reproductive techniques, medicinal plants have been utilized to treat male infertility. Medicinal plants, ... -
The in vitro effects of artificial and natural sweeteners on the immune system using whole blood culture assays
(Taylor & Francis, 2013)This article investigates the effects of commercially available artificial (aspartame, saccharin, sucralose) and natural sweeteners (brown sugar, white sugar, molasses) on the immune system. Human whole blood cultures ... -
In vitro evaluation of the anti-diabetic potential of aqueous acetone Helichrysum petiolare extract (AAHPE) with molecular docking relevance in diabetes mellitus
(MDPI, 2021-12)Diabetes mellitus (DM) is a chronic metabolic condition that can lead to significant complications and a high fatality rate worldwide. Efforts are ramping up to find and develop novel α-glucosidase and α-amylase inhibitors ...