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Multi-targeted directed ligands for Alzheimer’s disease: design of novel lead coumarin conjugates
(Taylor & Francis, 2018)
Alzheimer’s Disease (AD) is a neurodegenerative disease characterized by central nervous system insults with progressive cognitive (memory, attention) and non-cognitive (anxiety, depression) impairments. Pathophysiological ...
Microtubular dysfunction and male infertility
(Korean Society for Sexual Medicine and Andrology, 2018)
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and
cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain ...
B-cell and T-cell activation in South African HIV-1-positive non-Hodgkin’s lymphoma patients
(AOSIS, 2018)
BACKGROUND: Altered immune mechanisms play a critical role in the pathogenesis of non-
Hodgkin’s lymphoma (NHL). HIV-1 (HIV) infection is associated with a state of excessive
T-cell activation, which can lead to increased ...
Prerace medical screening and education reduce medical encounters in distance road races: SAFER VIII study in 153 208 race starters
(BMJ Publishing Group, 2018)
OBJECTIVES To examine the efficacy and feasibility of an online prerace medical screening and educational intervention programme for reducing medical complications in long-distance races.
METHODS This was an 8-year ...
Mathematical analysis and numerical simulation of a tumor-host model with chemotherapy application
(Communications in Mathematical Biology and Neuroscience, 2018)
In this paper, a system of non-linear quasi-parabolic partial differential system, modeling the chemotherapy application of spatial tumor-host interaction is considered. At some certain parameters, we derive the steady ...
Geometagenomics illuminates the impact of agriculture on the distribution and prevalence of plant viruses at the ecosystem scale
(Nature Publishing Group, 2018)
Disease emergence events regularly result from human activities such as agriculture, which
frequently brings large populations of genetically uniform hosts into contact with potential
pathogens. Although viruses cause ...
Siphonophores from surface waters of the Colombian Pacific Ocean
(Cambridge University Press, 2018)
Siphonophores are colonial hydrozoans that feed on zooplankton including fish larvae, and occur throughout the world’s oceans from surface waters to ocean depths. Here we describe the composition of hyponeustonic siphonophores ...
Modelling the rotation period distribution of M dwarfs in the Kepler field
(Springer Verlag, 2018)
McQuillan et al. (Mon. Not. R. Astron. Soc.432:1203, 2013) presented 1570 periods P of M dwarf stars in the field of view of the Kepler telescope. It is expected that most of these reflect rotation periods, due to starspots. ...
Characterization of macropore structure of Malan loess in NW China based on 3D pipe models constructed by using computed tomography technology
(Elsevier, 2018)
Malan loess is a grayish yellow or brownish yellow, clastic, highly porous and brittle late Quaternary sediment formed by the accumulation of windblown dust. The present-day pore structure of Malan loess is crucial for ...
A comparison of Einstein-Boltzmann solvers for testing General Relativity
(American Physical Society, 2018)
We compare Einstein-Boltzmann solvers that include modifications to General Relativity and find that, for a
wide range of models and parameters, they agree to a high level of precision. We look at three general purpose
codes ...