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Now showing items 11-20 of 25
Chromosomal-level assembly of the Asian seabass genome using long sequence reads and multi-layered scaffolding
(Public Library of Science, 2016)
We report here the ~670 Mb genome assembly of the Asian seabass (Lates calcarifer), a
tropical marine teleost. We used long-read sequencing augmented by transcriptomics, optical
and genetic mapping along with shared ...
The African Coelecanth genome provides insights into tetrapod evolution
(Macmillan Publishers, 2013)
The discovery of a living coelacanth specimen in 1938 was remarkable, as this lineage of lobe-finned fish was thought to have become extinct 70 million years ago. The modern coelacanth looks remarkably similar to many of ...
A uniquely African focus: bioinformatics is a field that has grown exponentially in the past few years, and it is becoming increasingly important to collaborate as the field continues to gather momentum
(2015)
Bioinformatics is a field that has grown exponentially in the past few years, and it is becoming increasingly important to collaborate as the field continues to gather momentum.
Challenges of biobanking in South Africa to facilitate indigenous research in an environment burdened with human immunodeficiency virus, tuberculosis, and emerging non-communicable diseases
(Mary Ann Liebert, Inc., 2013)
The high burden of infectious diseases and the growing problem of noncommunicable and metabolic disease syndromes in South Africa (SA) forces a more focused research approach to facilitate cutting-edge scientific growth ...
Taste and odorant receptors of the coelecanth- a gene repertoire in transition
(Wiley, 2014)
G-protein coupled chemosensory receptors (GPCR-CRs) aid in the perception of odors and tastes in vertebrates. So far, six GPCR-CR families have been identified that are conserved in most vertebrate species. Phylogenetic ...
Evolution and structural analysis of Glossina morsitans (Diptera; Glossinidae) Tetraspanins
(MDPI, Basel, Switzerland, 2014)
Tetraspanins are important conserved integral membrane proteins expressed in
many organisms. Although there is limited knowledge about the full repertoire, evolution and structural characteristics of individual members ...
DDPC: Dragon database of genes associated with prostate cancer
(Oxford Journals, 2011)
Prostate cancer (PC) is one of the most commonly diagnosed cancers in men. PC is relatively difficult to diagnose due to a lack of clear early symptoms. Extensive research of PC has led to the availability of a large amount ...
Inferring bona fide transfrags in RNA-Seq derived-transcriptome assemblies of non-model organisms
(BioMed Central, 2015)
Background: De novo transcriptome assembly of short transcribed fragments (transfrags) produced from sequencing-by-synthesis technologies often results in redundant datasets with differing levels of unassembled, partially ...
Molecular evolution of key receptor genes in primates and non-human primates
(Science Publishing Group, 2014)
African primates remain an unexplored source of information required to complete the origin and evolution of many human pathogens. Current studies have shown the importance of several receptor human genes implicated in ...
A glance at quality score: implication for de novo transcriptome reconstruction of Illumina reads
(Frontiers, 2014)
Downstream analyses of short-reads from next-generation sequencing platforms are often preceded by a pre-processing step that removes uncalled and wrongly called bases. Standard approaches rely on their associated base ...