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Now showing items 11-16 of 16
Reactive oxygen species in male reproduction: A boon or a bane?
(Wiley, 2020)
Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ...
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2020)
Oxidative stress is pre‐empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ...
Ritalinic acid stimulates human sperm motility and maintains vitality in vitro
(Korean Society for Sexual Medicine and Andrology, 2020)
To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. Materials and Methods: ...
Alpha-glucosidase and alpha-amylase inhibitory activities, molecular docking, and antioxidant capacities of salvia aurita constituents
(MPDI, 2020)
Diabetes mellitus (DM) is one of the most dangerous metabolic diseases with a high rate of mortality worldwide. It is well known that insulin resistance and deficiency in insulin production from pancreatic β-cells are the ...
Differential sensitivity of two endothelial cell lines to hydrogen peroxide toxicity: Relevance for in vitro studies of the blood–brain barrier
(MPDI, 2020)
Oxidative stress (OS) has been linked to blood–brain barrier (BBB) dysfunction which in
turn has been implicated in the initiation and propagation of some neurological diseases. In this study,
we profiled, for the first ...
Critical evaluation of two models of flow cytometers for the assessment of sperm DNA fragmentation: an appeal for performance verification
(Medknow Publications, 2019)
Lack of standardized, reproducible protocols and reference values is among the challenges faced when using new or upgraded
versions of instruments in reproductive laboratories and flow cytometry. Terminal deoxynucleotidyl ...