Browsing Biotechnology by Issue Date
Now showing items 41-60 of 215
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Drought and exogenous abscisic acid alter hydrogen peroxide accumulation and diferentially regulate the expression of two maize RD22-like genes
(Nature Research, 2017)Increased biosynthesis of abscisic acid (ABA) occurs in plants in response to water defcit, which is mediated by changes in the levels of reactive oxygen species such as H2O2. Water defcit and ABA induce expression of ... -
Drought and salinity stress alters ROS accumulation, water retention, and osmolyte content in sorghum plants
(Elsevier, 2017)biotic stresses such as drought and salinity are major environmental factors that influence crop productivity worldwide. These adverse conditions induce osmotic stresses in plant cells by decreasing water availability, thus ... -
Genetic variation and population structure of Botswana populations as identified with AmpFLSTR Identifiler short tandem repeat (STR) loci
(Nature Publishing Group, 2017-07-28)Population structure was investigated in 990 Botswana individuals according to ethno-linguistics, Bantu and Khoisan, and geography (the nine administrative districts) using the Identifiler autosomal microsatellite markers. ... -
Molecular application of aptamers in the diagnosis and treatment of cancer and communicable diseases
(MDPI, 2018)Cancer and infectious diseases such as Ebola, HIV, tuberculosis, Zika, hepatitis, measles and human schistosomiasis are serious global health hazards. The increasing annual morbidities and mortalities of these diseases ... -
Inhibition of NOS- like activity in maize alters the expression of genes involved in H2O2 scavenging and glycine betaine biosynthesis
(Nature Publishing Group, 2018)Nitric oxide synthase-like activity contributes to the production of nitric oxide in plants, which controls plant responses to stress. This study investigates if changes in ascorbate peroxidase enzymatic activity and ... -
Adapting the yeast consolidated bioprocessing paradigm for biorefineries
(Green Wave Publishing of Canada, 2018)Despite decades long development, no natural or engineered organism has been isolated that can produce commodity products at the rates and yields required by industry via direct microbial conversion. However, new genomic ... -
Taxonomy of prokaryotic viruses: 2017 update from the ICTV Bacterial and Archaeal Viruses Subcommittee
(Springer, 2018)The prokaryotic virus community is represented at the International Committee on Taxonomy of Viruses (ICTV) by the Bacterial and Archaeal Viruses Subcommittee. Since our last report [5], the committee composition has ... -
Factors influencing pigment production by halophilic bacteria and its effect on brine evaporation rates
(Wiley, 2018)The disposal of reject brine, a highly concentrated waste by-product generated by various industrial processes, represents a major economic and environmental challenge. The common practice in dealing with the large ... -
Brown rot-type fungal decomposition of sorghum bagasse: variable success and mechanistic implications
(Hindawi Publishing Corporation, 2018)Sweet sorghum is a promising crop for a warming, drying African climate, and basic information is lacking on conversion pathways for its lignocellulosic residues (bagasse). Brown rot wood-decomposer fungi use carbohydra ... -
Efficient superoxide scavenging and metal immobilization in roots determines the level of tolerance to vanadium stress in two contrasting Brassica napus genotypes
(Elsevier, 2018)Brassica napus also known as Rapeseed is a member of the Brassicaceae family which is mainly cultivated for its oil-rich seeds. Indeed, B. napus is ranked the third-largest source of vegetable oil in the world. Brassica ... -
PZQ Therapy: How close are we in the development of effective alternative anti-schistosomal drugs?
(Bentham Science Publishers, 2019)Today schistosomiasis, caused mainly by the three major schistosome species (S. mansoni, S. haematobium and S. japonicum), has for many decades and still continues to be on a rapid and swift rise globally, claiming ... -
Forensic parameters and genetic structure based on Y-chromosome short tandem repeats in Lesotho populations
(Forensic Science International: Genetics Supplement Series, 2019)Lesotho is a landlocked country with approximately 2.2 million inhabitants. Over 97% of the population is represented by the Southern Sotho people (Sotho-Tswana group), followed by a number of minorities mostly from the ... -
UniQ-Typer ™ Y-10 genotyping in South African populations: novel alleles, sequence variation and allelic ladder updates
(Elsevier, 2019)DNA profiling the male specific region on the Y-chromosome is fundamental to forensic practise. It is recognised as a powerful tool for sexual assault investigations for resolving the male DNA components, for familial ... -
Structural analysis, molecular modelling and preliminary competition binding studies of AM-DAN as a NMDA receptor PCP-Site fluorescent ligand
(MDPI, 2019): Excitotoxicity related to the dysfunction of the N-methyl-d-aspartate receptor (NMDAR) has been indicated to play an integral role in the pathophysiology of multiple disease states, including neurodegenerative disorders ... -
Exogenous p-coumaric acid improves salvia hispanica l. Seedling shoot growth
(MDPI Open Access Journals, 2019)p-Coumaric acid (p-CA) belongs to a family of natural esters of hydroxycinnamic acid compounds that have been shown to modulate plant growth and metabolism. In this study, we investigated the effect of exogenous p-CA on ... -
Forensic science international: genetics supplement series
(ScienceDirect, 2019)We have designed a buffer for preservation of DNA in biological material at room temperature. In this work we evaluated the integrity of DNA from saliva, stored for 4 years and blood stored for 4 months at room temperature. ... -
An in vitro study on the combination effect of metformin and n-acetyl cysteine against hyperglycaemia-induced cardiac damage
(MDPI - Publisher of Open Access Journals, 2019)Chronic hyperglycaemia is a major risk factor for diabetes-induced cardiovascular dysfunction. In a hyperglycaemic state, excess production of reactive oxygen species (ROS), coupled with decreased levels of glutathione, ... -
Genetic landscape of the mitochondrial DNA control region in South African populations
(ScienceDirect, 2019)A high-quality dataset of the mitochondrial DNA control region sequences was generated with Sanger and next-generation sequencing. The study was aimed at characterizing the maternal genetic ancestry and analyzing the ... -
In silico identification of micrornas as candidate Colorectal cancer biomarkers
(Sage Journals, 2019)The involvement of microRNA in cancers plays a significant role in their pathogenesis. Specific expressions of these non-coding RNAs also serve as biomarkers for early colorectal cancer diagnosis, but their laboratory/molecular ... -
Improved cellulase expression in diploid yeast strains enhanced consolidated bioprocessing of pretreated corn residues
(ScienceDirect, 2019)In an effort to find a suitable genetic background for efficient cellulolytic secretion, genetically diverse strains were transformed to produce core fungal cellulases namely, β-glucosidase (BGLI), endoglucanase (EGII) and ...