Browsing Biotechnology by Title
Now showing items 1-20 of 79
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Adapting the yeast consolidated bioprocessing paradigm for biorefineries
(Green Wave Publishing of Canada, 2018)Despite decades long development, no natural or engineered organism has been isolated that can produce commodity products at the rates and yields required by industry via direct microbial conversion. However, new genomic ... -
The air quality perceptions of the residents of Bayview, Mossel Bay
(NACA, 2014)Background: In developing countries, it often occurs that little attention is given to air pollution emissions due to a lack of proper town planning, household combustion processes, energy production and the continuous ... -
Alteration of Bax-to-Bcl-2 ratio modulates the anticancer activity of methanolic extract of Commelina benghalensis (Commelinaceae) in Jurkat T cells
(Academic Journals, 2008)Stem extracts of Commelina benghalensis (Linn.), although not extensively documented, are frequently used in traditional medicine for the treatment of ailments such as skin malformations and outgrowths. Accordingly, the ... -
Antibacterial activity of biogenic silver and gold nanoparticles synthesized from Salvia africana-lutea and Sutherlandia frutescens
(Nanotechnology, 2020)Nanoparticles (NPs) synthesized using various chemical and physical methods are often cytotoxic which restricts their use in biomedical applications. In contrast, metallic biogenic NPs synthesized using biological systems ... -
Antibacterial activity of rationally designed antimicrobial peptides.
(Hindawi, 2020)Many infectious diseases are still prevalent in the world’s populations since no effective treatments are available to eradicate them. e reasons may either be the antibiotic resistance towards the available therapeutic ... -
Apoptosis in cancer cells is induced by alternative splicing of hnrnpa2/b1 through splicing of bcl-x, a mechanism that can be stimulated by an extract of the South African medicinal plant, cotyledon orbiculata
(Frontiers Media S.A., 2020)Alternative splicing is deregulated in cancer and alternatively spliced products can be linked to cancer hallmarks. Targeting alternative splicing could offer novel effective cancer treatments. We investigated the effects ... -
Applications of computational methods in biomedical breast cancer imaging diagnostics: A review
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ... -
Applications of computational methods in biomedical Breast cancer imaging diagnostics: A review
(MDPI, 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ... -
Applications of Computational Methods in Biomedical Breast Cancer Imaging Diagnostics: A Review
(MDPI, 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ... -
Aptamer-Based Diagnostic Systems for the Rapid Screening of TB at the Point-of-Care
(MDPI, 2021)The transmission of Tuberculosis (TB) is very rapid and the burden it places on health care systems is felt globally. The effective management and prevention of this disease requires that it is detected early. Current TB ... -
Assessment of temporal and spatial evolution of bacterial communities in a biological sand filter mesocosm treating winery wastewater
(The Society for Applied Microbiology, 2013)AIMS: To assess the impact of winery wastewater (WW) on biological sand filter (BSF) bacterial community structures, and to evaluate whether BSFs can constitute alternative and valuable treatment-processes to remediate WW. ... -
Association analysis of two single-nucleotide polymorphisms of the RELN gene with autism in the South African population
(Mary Ann Liebert, Inc., 2013)BACKGROUND: Autism (MIM209850) is a neurodevelopmental disorder characterized by a triad of impairments, namely impairment in social interaction, impaired communication skills, and restrictive and repetitive behavior. A ... -
Balancing redox cofactor generation and ATP synthesis: key microaerobic responses in thermophilic fermentations
(Wiley, 2013)Geobacillus thermoglucosidasius is a Grampositive, thermophilic bacterium capable of ethanologenic fermentation of both C5 and C6 sugars and may have possible use for commercial bioethanol production [Tang et al., 2009; ... -
Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer
(MDPI, 2021)The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies. Anticancer peptides (ACPs) are a subset of host ... -
Brown rot-type fungal decomposition of sorghum bagasse: variable success and mechanistic implications
(Hindawi Publishing Corporation, 2018)Sweet sorghum is a promising crop for a warming, drying African climate, and basic information is lacking on conversion pathways for its lignocellulosic residues (bagasse). Brown rot wood-decomposer fungi use carbohydra ... -
Capacity to control oxidative stress-induced caspase-like activity determines the level of tolerance to salt stress in two contrasting maize genotypes
(Springer, 2013)The response of two maize (Zea mays L.) genotypes, named GR (salt-tolerant) and SK (salt-sensitive), to salt stress (150 mM NaCl) was investigated under controlled environmental growth conditions. Genotype SK experienced ... -
Cheminformatic Characterization of Natural Antimicrob al Products for the Development of New Lead Compounds
(MDPI, 2021)The growing antimicrobial resistance (AMR) of pathogenic organisms to currently pre- scribed drugs has resulted in the failure to treat various infections caused by these superbugs. Therefore, to keep pace with the ... -
Comparative analysis of responses to field salinity stress in contrasting soybean accessions highlights NaCl exclusion in leaves as a key mechanism for salinity stress tolerance.
(JOURNAL OF OASIS AGRICULTURE AND SUSTAINABLE DEVELOPMENT, 2021)Salinity is one of the main limitations to legume productivity in many regions of the world and it is estimated that 50% of all arable land will become affected by salinity by 2050. The impact of field salinity on soybean ... -
Comparative whole corona fingerprinting and protein adsorption thermodynamics of PLGA and PCL nanoparticles in human serum
(Elsevier, 2020)Nanoparticles (NPs) based on biocompatible and biodegradable polymers such as poly(lactic-co-glycolic acid) (PLGA) and polycaprolactone (PCL) represent effective systems for systemic drug delivery. Upon injection into the ... -
Cross-sectional study of prevalence and determinants of uncontrolled hypertension among South African adult residents of Mkhondo municipality
(Springer Nature, 2020)Achieving the blood pressure treatment target in individuals with hypertension is a serious global health challenge. Furthermore, the actual burden of uncontrolled hypertension is poorly understood, especially in the ...
