Browsing Biotechnology by Author "Madiehe, Abram Madimabe"
Now showing items 1-5 of 5
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The antimicrobial and anti-inflammatory effects of silver nanoparticles synthesised from cotyledon orbiculata aqueous extract
Tyavambiza, Caroline; Elbagory, Abdulrahman Mohammed; Madiehe, Abram Madimabe (MDPI, 2021)Cotyledon orbiculata, commonly known as pig’s ear, is an important medicinal plant of South Africa. It is used in traditional medicine to treat many ailments, including skin eruptions, abscesses, inflammation, boils and ... -
The antioxidant and in vitro wound healing activity of cotyledon orbiculata aqueous extract and the synthesized biogenic silver nanoparticles
Tyavambiza, Caroline; Meyer, Mervin; Madiehe, Abram Madimabe (MDPI, 2022)The synthesis of silver nanoparticles using biogenic methods, particularly plants, has led to the discovery of several effective nanoparticles. In many instances, plant-derived silver nanoparticles have been shown to ... -
Computational insight of dexamethasone against potential targets of SARS-CoV-2
Fadaka, Adewale Oluwaseun; Sibuyi, Nicole Remaliah Samantha; Madiehe, Abram Madimabe (Taylor and Francis Group, 2022)The health sector has been on the race to find a potent therapy for coronavirus disease (COVID)-19, a diseases caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2. Repurposed anti-viral drugs have played ... -
MicroRNA-based regulation of Aurora A kinase in breast cancer
Sibuyi, Nicole Remaliah Samantha; Fadaka, Adewale Oluwaseun; Madiehe, Abram Madimabe (Impact Journals, 2020)The involvement of non-coding RNAs (ncRNAs) in cellular physiology and disease pathogenesis is becoming increasingly relevant in recent years specifically in cancer research. Breast cancer (BC) has become a health concern ... -
Nanotechnology-based delivery systems for antimicrobial peptides
Adewale, Oluwaseun Fadaka; Sibuyi, Nicole Remaliah Samantha; Madiehe, Abram Madimabe; Meyer, Mervin (MDPI, 2021)Antimicrobial resistance (AMR) is a significant threat to global health. The conventional antibiotic pool has been depleted, forcing the investigation of novel and alternative antimicrobial strategies. Antimicrobial peptides ...