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Human sperm handling in intracytoplasmic sperm injection processes: In vitro studies on mouse oocyte activation, embryo development competence and sperm oxidation–reduction potential
(Wiley, 2018)
Polyvinylpyrrolidone (PVP) and hyaluronic acid (HA) are routinely used in handling spermatozoa for intracytoplasmic sperm injection (ICSI). As there are still concerns about possible adverse effects on the embryo, this ...
Autosomal recessive congenital cataract in captive-bred vervet monkeys (Chlorocebus aethiops)
(Wiley, 2018)
BACKGROUND: The aim of the study was to evaluate the genetic predisposition of congenital cataract in a colony of captive-bred vervet monkeys.
METHODS: Four congenital cataract genes: glucosaminyl (N-acetyl) transferase ...
The excessive use of antioxidant therapy: A possible cause of male infertility?
(Wiley, 2018)
Reactive oxygen species and oxidative stress are closely associated with various pathologies such as neurodegenerative diseases, ageing and male infertility. Hence, antioxidants such as vitamin C, vitamin E, N‐acetyl ...
Group B streptococcus serotypes in pregnant women from the Western Cape region of South Africa
(Frontiers, 2018-12-04)
Background: Maternal colonization of Group B streptococci (GBS) during pregnancy is an important risk factor for neonatal morbidity and mortality. The aim of this study was to determine the prevalence and serotype distribution ...
The effects of carbon dots on immune system biomarkers, using the Murine Macrophage cell line RAW 264.7 and human whole blood cell cultures
(MDPI, 2018)
Abstract: Carbon dots (CDs) are engineered nanoparticles that are used in a number of bioapplications
such as bioimaging, drug delivery and theranostics. The effects of CDs on the immune system have
not been evaluated. ...
Rutin as a potent antioxidant: implications for neurodegenerative disorders
(Hindawi Publishing Corporation, 2018)
A wide range of neurodegenerative diseases (NDs), including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and
prion diseases, share common mechanisms such as neuronal loss, apoptosis, mitochondrial ...
Vaginal microbiomes associated with aerobic vaginitis and bacterial vaginosis
(Frontiers Media, 2018)
A healthy vaginal microbiota is considered to be significant for maintaining vaginal health
and preventing infections. However, certain vaginal bacterial commensal species serve
an important first line of defense of the ...
Eco-friendly synthesis, characterization, in vitro and in vivo anti-inflammatory activity of silver nanoparticle-mediated Selaginella myosurus aqueous extract
(Dovepress, 2018)
Introduction: There is emerging interest in medicinal plants in the biomedical field, due to their
multitude of chemicals which show anti-inflammatory, antimicrobial, antiviral, or antitumoral
potential. Research on ...
Acute toxicity studies of the South African medicinal plant Galenia africana
(Elsevier, 2018)
Background: Medicinal plants are used by a large proportion of the global population as complementary and
alternative medicines. However, little is known about their toxicity. G. africana has been used to treat wounds,
coughs ...
Quantitative assessment of heavy metal effects on sperm function using computer‐aided sperm analysis and cytotoxicity assays
(Wiley, 2018)
One known environmental risk factor impacting on human reproduction is heavy metal pollution. Although some metals (e.g., Cu, Se and Zn) have protective effects on the male reproductive system in low doses, heavy metals ...