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Structure based identification of novel inhibitors against ATP synthase of Mycobacterium tuberculosis: A combined in silico and in vitro study
(International Journal of Biological Macromolecules, 2019)
The shortcomings of conventional tuberculosis treatments resulting from the development of drug resistance in
Mycobacteriumtuberculosis drive a need for the formulation of novel therapeutic agents. The diarylquinoline ...
Designing novel possible kinase inhibitor derivatives as therapeutics against Mycobacterium tuberculosis: An in silico study
(Scientific Reports, 2019)
Rv2984 is one of the polyphosphate kinases present in Mycobacterium tuberculosis involved in the
catalytic synthesis of inorganic polyphosphate, which plays an essential role in bacterial virulence
and drug resistance. ...
Capacity building for whole genome sequencing of Mycobacterium tuberculosis and bioinformatics in high TB burden countries
(Oxford University Press, 2020)
Background
Whole-genome sequencing (WGS) is increasingly used for Mycobacterium tuberculosis (Mtb) research. Countries with the highest tuberculosis (TB) burden face important challenges to integrate WGS into surveillance ...