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Human Leukocyte Antigen-A, B, C, DRB1, and DQB1 Allele and Haplotype Frequencies in a subset of 237 donors in the South African Bone Marrow Registry
(Hindawi, 2018)
Human leukocyte antigen- (HLA-) A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 allele and haplotype frequencies were studied in a subset of 237 volunteer bone marrow donors registered at the South African Bone Marrow Registry ...
Odorant and gustatory receptors in the tsetse fly Glossina morsitans morsitans
(PLOS, 2014)
Tsetse flies use olfactory and gustatory responses, through odorant and gustatory receptors (ORs and GRs), to interact with their environment. Glossina morsitans morsitans genome ORs and GRs were annotated using homologs ...
Human African trypanosomiasis research gets booost: unravelling the tsetse Genome
(PLOS, 2014)
Human African trypanosomiasis (HAT), also known as sleeping sickness, is a neglected disease that impacts 70 million people distributed over 1.55 million km2 in sub-Saharan Africa. Trypanosoma brucei gambiense accounts for ...
International Glossina Genome Initiative 2004-2014: a driver for post-genomic era research on the African continent
(PLOS, 2014)
Human African trypanosomiasis (HAT), also known as sleeping sickness, is a neglected disease that impacts 70 million people distributed over 1.55 million km2 in sub- Saharan Africa and includes at least 50% of the population ...
Genome sequence of the tsetse fly (glossina morsitans): vector of African trypanosomiasis
(American Association for the Advancement of Science, 2014)
Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa.
Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable
differences between ...
Defining the molecular signatures of Achilles tendinopathy and anterior cruciate ligament ruptures: A whole-exome sequencing approach
(Public Library of Science, 2018)
Musculoskeletal soft tissue injuries are complex phenotypes with genetics being one of
many proposed risk factors. Case-control association studies using the candidate gene
approach have predominately been used to identify ...
The westward journey of alfalfa leaf curl virus
(MDPI, 2018)
Alfalfa leaf curl virus (ALCV), which causes severe disease symptoms in alfalfa (Medicago
sativa L.) and is transmitted by the widespread aphid species, Aphis craccivora Koch, has been
found throughout the Mediterranean ...
Geometagenomics illuminates the impact of agriculture on the distribution and prevalence of plant viruses at the ecosystem scale
(Nature Publishing Group, 2018)
Disease emergence events regularly result from human activities such as agriculture, which
frequently brings large populations of genetically uniform hosts into contact with potential
pathogens. Although viruses cause ...
An integrated and comparative approach towards identification, characterization and functional annotation of candidate genes for drought tolerance in sorghum (Sorghum bicolor (L.) Moench)
(BioMed Central, 2017)
BACKGROUND: Drought is the most disastrous abiotic stress that severely affects agricultural productivity worldwide.
Understanding the biological basis of drought-regulated traits, requires identification and an in-depth ...
Structural rearrangements maintain the Glycan Shield of an HIV-1 envelope trimer after the loss of a glycan
(Nature Research, 2018)
The HIV-1 envelope (Env) glycoprotein is the primary target of the humoral immune response and a
critical vaccine candidate. However, Env is densely glycosylated and thereby substantially protected
from neutralisation. ...