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Now showing items 1626-1645 of 7879
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Design and synthesis of acyldepsipeptide-1 analogues: antibacterial activity and cytotoxicity screening
(Arabian Journal of Chemistry, 2023)Acyldepsipeptides (ADEPs) are receiving more attention as prospective antimicrobial agents due to their unique mode of action and chemical properties. However, their therapeutic potential is limited by their poor pharmacokinetic ... -
Design principles for interdisciplinary collaborative learning through social, digital innovation
(Universitat Politecnica de Valencia, Valencia, 2021)As academics, we are acutely aware of our responsibility in the design of our teaching and learning environment to instil principles of ethics, sustainability, agency and social justice. We are at the crossroad between ... -
The design, development & implementation of an In-house SRS to enhance the teaching & learning experience: Case-study of the University of the Western Cape
(University of the Western Cape, 2016)The Centre for Innovative Education & Communication Technologies at UWC has designed a Student Response System (SRS), which will enable students to respond electronically to questions posed by the lecturer during a class ... -
Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer’s disease agents
(Taylor & Francis Open Access, 2021)Multitarget directed ligands (MTDLs) are emerging as promising treatment options for Alzheimer’s disease (AD). Coumarin derivatives serve as a good starting point for designing MTDLs due to their inherent inhibition of ... -
A designed experiments approach to optimizing MALDI-TOF MS spectrum processing parameters enhances detection of antibiotic resistance in Campylobacter jejuni
(Frontiers Media, 2016)MALDI-TOF MS has been utilized as a reliable and rapid tool for microbial fingerprinting at the genus and species levels. Recently, there has been keen interest in using MALDI-TOF MS beyond the genus and species levels to ... -
Designing a course model for distance-based online bioinformatics training in Africa: the H3ABioNet experience
(Public Library of Science, 2017)Africa is not unique in its need for basic bioinformatics training for individuals from a diverse range of academic backgrounds. However, particular logistical challenges in Africa, most notably access to bioinformatics ... -
Designing a social work online self-coaching program: Integrated support and joint ownership
(2017)The paper explores Critical Success Factors (CSFs) in relation to the support structure for an online self-coaching pilot project, by the Centre for Innovative Education and Communication Technologies (CIECT) of the ... -
Designing an Arabic speaking and listening skills e-course: resources, activities and students’ perceptions
(Academic Conferences and Publishing International Limited, 2021)his paper presents a fully online course model for teaching speaking and listening skills for students learning Arabic as a foreign language at the International Peace College South Africa on the NEO learning management ... -
Designing an optimal LSST deep drilling program for cosmology with type Ia supernovae
(American Astronomical Society, 2023)The Vera C. Rubin Observatory’s Legacy Survey of Space and Time (LSST) is forecast to collect a large sample of Type Ia supernovae (SNe Ia) expected to be instrumental in unveiling the nature of dark energy. The feat, ... -
Designing mobile phone interfaces for age diversity in South Africa: “One-World” versus diverse “Islands”
(Springer, 2013)Designing for diversity is a laudable aim. How to achieve this, in the context of mobile phone usage by South African seniors, is a moot point. We considered this question from two possible perspectives: universal ... -
Designing novel possible kinase inhibitor derivatives as therapeutics against Mycobacterium tuberculosis: An in silico study
(Scientific Reports, 2019)Rv2984 is one of the polyphosphate kinases present in Mycobacterium tuberculosis involved in the catalytic synthesis of inorganic polyphosphate, which plays an essential role in bacterial virulence and drug resistance. ... -
Designing online learning environments in higher education: Building capacity of lecturers to design and facilitate blended e-pedagogy for mature students
(University of the Western Cape, 2022)Amidst the spread of COVID-19, higher education institutions (HEIs) in South Africa were compelled to offer academic programmes through online learning by utilising digital information and communication technologies (ICT) ... -
Designing the project: theoretical approaches
(HSRC Press, 2012)Education in South Africa is in crisis. Low literacy and numeracy rates, poor discipline, and a sense of despair pervade the education landscape. At the same time, educators are called upon to achieve more, with universities ... -
Designing theoretical assessments at nursing higher education institutions: A scoping review
(Stellenbosch University, 2022)Assessment in higher education remains one of the most reliable forms of assessing the effectiveness of the learning and teaching (L&T) process. Excellence in theory assessment design is, therefore, a pivotal element of ... -
Desire and language in Derrida’s 'Force of Law'
(Franz Steiner Verlag, 2009)In this article, the author proposes a reading of 'Force of Law' from two angles: boundless desire and the ‘law’ of language. The author contends that an analysis from these perspectives casts new light on the notion of ... -
Desperate times call for desperate measures: Adapting antiretroviral service delivery in the context of the COVID-19 pandemic
(SAMA, 2020)On 23 March 2020, President Cyril Ramaphosa announced a nation-wide lockdown to help curb the spread of the COVID-19 epidemic in South Africa (SA). While these containment measures are considered to have limited the ... -
The detailed forms of the LMC Cepheid PL and PLC relations
(Oxford University Press, 2007)Possible deviations from linearity of the Large Magellanic Cloud Cepheid period–luminosity (PL) and period–luminosity–colour (PLC) relations are investigated. Two data sets are studied, respectively from the Optical ... -
Detecting marine heatwaves with sub-optimal data
(Frontiers, 2019)Marine heatwaves (MHWs), or prolonged periods of anomalously warm sea water temperature, have been increasing in duration and intensity globally for decades. However, there are many coastal, oceanic, polar, and sub-surface ... -
Detecting the relativistic galaxy bispectrum
(IOP Publishing Ltd, 2020)The Fourier galaxy bispectrum is complex, with the imaginary part arising from leading-order relativistic corrections, due to Doppler, gravitational redshift and related lineof-sight effects in redshift space. The detection ...