Browsing by Subject "Parkinson’s disease"
Now showing items 1-8 of 8
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Antioxidant and apoptosis-inhibition potential of Carpobrotus edulis in a model of parkinson’s disease
(African Association of Physiological Sciences, 2018)Background: Parkinson’s disease (PD) is a neurological disorder resulting from the progressive loss of dopaminergic neurons. There is currently no known cure for PD, thus the search for complementary and alternative medicines ... -
Cost-effectiveness of the HiBalance training program for elderly with Parkinson’s disease: analysis of data from a randomized controlled trial
(SAGE Publications, 2018)OBJECTIVE: To determine the cost-effectiveness of the HiBalance training program for managing Parkinson’s disease (PD)-related balance and gait disorders. DESIGN: Cost comparison design following the randomized controlled ... -
Current Status of Next-Generation Sequencing Approaches for Candidate Gene Discovery in Familial Parkinson´s Disease
(Frontiers in Genetics, 2022)Parkinson’s disease is a neurodegenerative disorder with a heterogeneous genetic etiology. The advent of next-generation sequencing (NGS) technologies has aided novel gene discovery in several complex diseases, including ... -
Implementation of the HiBalance training program for Parkinson’s disease in clinical settings: A feasibility study
(Wiley Open Access, 2018)BACKGROUND: Translating evidence into practice requires adaptation to facilitate the implementation of efficacious interventions. A novel highly challenging balance training program (HiBalance) was found to improve gait, ... -
Neuroprotective activities of Boophone haemanthoides (amaryllidaceae) extract and its chemical constituents
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)Parkinson’s disease (PD) is a neurodegenerative condition that progresses as age increases, and some of its major symptoms include tremor and postural and movement-related difficulties. To date, the treatment of PD remains ... -
Neuroprotective Activities of Crossyne flava Bulbs and Amaryllidaceae Alkaloids: Implications for Parkinson’s Disease
(MDPI, 2021)Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and affects approximately 6.3 million people worldwide. To date, the treatment of PD remains a challenge, as available treatment options are ... -
Patient-Control Association Study of the Leucine-Rich Repeat Kinase 2 (LRRK2) Gene in South African Parkinson's Disease Patients
(National Institute of Health, 2013)The leucine-rich repeat kinase 2 (LRRK2) gene is of interest to Parkinson's disease (PD) as it has been implicated in both familial and sporadic forms of the disorder.1 PD-susceptibility alleles in LRRK2 appear to be ... -
Using functional near-infrared spectroscopy to measure prefrontal cortex activity during dual-taskwalking and navigated walking: A feasibility study
(Wiley, 2023)While functional near-infrared spectroscopy (fNIRS) can provide insight into motor-cognitive deficits during ecologically valid gait conditions, the feasibility of using fNIRS during complex walking remains unknown.We ...