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Semiquantitative promoter methylation of MLH1 and MSH2 genes and their impact on sperm DNA fragmentation and chromatin condensation in infertile men
(Blackwell Publishing Ltd, 2021)
To investigate the semiquantitative methylation alterations of MLH1 and MSH2 and the possible association among methylation of MLH1 and MSH2, sperm DNA fragmentation and sperm chromatin condensation in idiopathic ...
Editorial commentary on draft of world health organization sixth edition laboratory manual for the examination and processing of human semen
(Korean Society for Sexual Medicine and Andrology, 2021)
Semen examination is the cornerstone of the evaluation of male fertility potential. Despite its apparent
simplicity, it is a complex series of assessments with
highly variable results that are subject to interpretation. ...
The new 6th edition of the WHO laboratory manual for the examination and processing of human semen: Is it a step toward better standard operating procedure?
(Shanghai Institute Materia Medica, 2021)
Semen analysis (SA) remains the
cornerstone of male infertility evaluation
and should ideally be performed by an
accredited andrology laboratory or in
vitro fertilization (IVF) clinics based on
the standards defined ...
Obesity and metabolic syndrome associated with systemic inflammation and the impact on the male reproductive system
(John Wiley & Sons Ltd, 2019)
Obesity and metabolic syndrome (MetS) are global epidemics, driven by an obe‐sogenic environment. This is mediated by complex underlying pathophysiology, in which chronic inflammation is an important aetiological and ...
Reactive oxygen species in male reproduction: A boon or a bane?
(Wiley, 2020)
Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ...
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2020)
Oxidative stress is pre‐empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ...
Ritalinic acid stimulates human sperm motility and maintains vitality in vitro
(Korean Society for Sexual Medicine and Andrology, 2020)
To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. Materials and Methods: ...
Relevance of leukocytospermia and semen culture and its true place in diagnosing and treating male infertility
(Korean Society for Sexual Medicine and Andrology, 2021)
The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive
leukocytes at a concentration >1×106
/mL of semen. Granular leukocytes when activated are capable of ...
Role of cytocentrifugation combined with nuclear fast picroindigocarmine staining in detecting cryptozoospermia in men diagnosed with azoospermia
(Seoul: Korean Society for Sexual Medicine and Andrology, 2022)
Azoospermia is defined as the absence of spermatozoa in the pellet of a centrifuged semen sample. In fact, when a
basic semen analysis fails to detect sperm in the ejaculate, there is still the possibility of detecting ...
In vitro effects of aqueous extract of unfermented rooibos on human spermatozoa
(Wiley, 2022)
The inability to conceive is a baleful experience for thousands of couples worldwide. Among different well-known reproductive techniques, medicinal plants have been utilized to treat male infertility. Medicinal plants, ...