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Lenses and levels: the why, what and how of measuring health system drivers of women’s, children’s and adolescents’ health with a governance focus
(BMJ, 2019)
Health systems are critical for health outcomes as they
underpin intervention coverage and quality, promote users’
rights and intervene on the social determinants of health.
Governance is essential for health system ...
How to use relevant data for maximal benefit with minimal risk: Digital health data governance to protect vulnerable populations in low-income and middle- income countries
(BMJ Global Health, 2019)
Globally, the volume of private and personal digital data has massively increased, accompanied by rapid expansion in the generation and use of digital health data. These technological advances promise increased opportunity
for ...
A meta-analysis of public microarray data identifies gene regulatory pathways deregulated in peripheral blood mononuclear cells from individuals with Systemic Lupus Erythematosus compared to those without
(BioMed Central, 2017)
BACKGROUND: Systemic Lupus Erythematosus (SLE) is a complex, multi-systemic, autoimmune disease for which the
underlying aetiological mechanisms are poorly understood. The genetic and molecular processes underlying ...
Blood pressure gradients and cardiovascular risk factors in urban and rural populations in Abia State South Eastern Nigeria using the WHO STEPwise approach
(Public Library of Science, 2013)
Background: Developing countries of sub-Saharan Africa (SSA) face a double burden of non-communicable diseases (NCDs)
and communicable diseases. As high blood pressure (BP) is a common global cardiovascular (CV) disorder ...
A diverse array of genetic factors contribute to the pathogenesis of Systemic Lupus Erythematosus
(Biomed Central, 2013)
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease with variable clinical presentation
frequently affecting the skin, joints, haemopoietic system, kidneys, lungs and central nervous system. It can ...
Ethical and legal implications of whole genome and whole exome sequencing in African populations
(BioMed Central, 2013)
BACKGROUND: Rapid advances in high throughput genomic technologies and next generation sequencing are
making medical genomic research more readily accessible and affordable, including the sequencing of patient and
control ...
An e-consent framework for tiered informed consent for human genomic research in the global south, implemented as a REDCap template
(BMC Medics, 2022)
Research involving human participants requires their consent, and it is common practice to capture consent information
on paper and store those hard copies, presenting issues such as long-term storage requirements, ...
Record linkage for routinely collected health data in an African health information exchange
(Swansea University, 2023)
The Patient Master Index (PMI) plays an important role in management of patient information and
epidemiological research, and the availability of unique patient identifiers improves the accuracy when
linking patient ...
Covid-19 among adults living with HIV: Correlates of mortality among public sector healthcare users in Western Cape, South Africa
(Wiley, 2023)
Introduction: While a large proportion of people with HIV (PWH) have experienced SARS-CoV-2 infections, there is uncertainty
about the role of HIV disease severity on COVID-19 outcomes, especially in lower-income settings. ...