Browsing Faculty of Natural Sciences by Title
Now showing items 112-131 of 2571
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Antinociceptive and anti-Inflammatory activities of leaf methanol extract of cotyledon orbiculata L. (Crassulaceae)
(Hindawi, 2012)Leaf methanol extract of C. orbiculata L. was investigated for antinociceptive and anti-inflammatory activities using acetic acid writhing and hot-plate tests and carrageenan-induced oedema test in mice and rats, respectively. ... -
Antinociceptive, anti-inflammatory and antipyretic activities of the leaf methanol extract of ruta graveolens l. (rutaceae) in mice and rats
(African Networks Ethnomedicines, 2014)Ruta graveolens has been used to treat toothache, earache, rheumatism and fever with little scientific evidence corroborating these uses. The leaf methanol extract of Ruta graveolens was evaluated for antinociceptive ... -
Antioxidant and apoptosis-inhibition potential of Carpobrotus edulis in a model of parkinson’s disease
(African Association of Physiological Sciences, 2018)Background: Parkinson’s disease (PD) is a neurological disorder resulting from the progressive loss of dopaminergic neurons. There is currently no known cure for PD, thus the search for complementary and alternative medicines ... -
The antioxidant and in vitro wound healing activity of cotyledon orbiculata aqueous extract and the synthesized biogenic silver nanoparticles
(MDPI, 2022)The synthesis of silver nanoparticles using biogenic methods, particularly plants, has led to the discovery of several effective nanoparticles. In many instances, plant-derived silver nanoparticles have been shown to ... -
Antioxidant responses are associated with differences in drought tolerance between maize and sorghum
(Arid land institute, 2021)Drought is a major cause of decreased yield in crops worldwide. Sorghum (Sorghum bicolor) and maize (Zea mays) are two of the key crops in Africa serving as human food as well as livestock feed. For improved crop ... -
An∼600 pc View of the Strongly Lensed, Massive Main-sequence Galaxy J0901: A Baryon-dominated, Thick Turbulent Rotating Disk with a Clumpy Cold Gas Ring at z=2.259
(Institute of Physics, 2023)We present a high-resolution kinematic study of the massive main-sequence star-forming galaxy (SFG) SDSS J090122.37+181432.3 (J0901) at z = 2.259, using ∼0 36 Atacama Large Millimeter/submillimeter Array CO(3–2) and ∼0 ... -
An∼600 pc view of the strongly lensed, massive main-sequence galaxy j0901: A baryon-dominated, thick turbulent rotating disk with a clumpy cold gas ring at z=2.259
(American Astronomical Society, 2023)We present a high-resolution kinematic study of the massive main-sequence star-forming galaxy (SFG) SDSS J090122.37+181432.3 (J0901) at z = 2.259, using ∼0 36 Atacama Large Millimeter/submillimeter Array CO(3–2) and ∼0 ... -
Apoptosis in cancer cells is induced by alternative splicing of hnrnpa2/b1 through splicing of bcl-x, a mechanism that can be stimulated by an extract of the South African medicinal plant, cotyledon orbiculata
(Frontiers Media S.A., 2020)Alternative splicing is deregulated in cancer and alternatively spliced products can be linked to cancer hallmarks. Targeting alternative splicing could offer novel effective cancer treatments. We investigated the effects ... -
Application of an in silico approach identifies a genetic locus within ITGB2, and its interactions with HSPG2 and FGF9, to be associated with anterior cruciate ligament rupture risk
(Taylor and Francis Group, 2023)We developed a Biomedical Knowledge Graph model that is phenotype and biological functionaware through integrating knowledge from multiple domains in a Neo4j, graph database. All known human genes were assessed through ... -
Application of anin silicoapproach identifies a genetic locus withinITGB2,and itsinteractions withHSPG2 and FGF9,to be associated with anterior cruciateligament rupture risk
(Taylor and Francis Group, 2023)We developed a Biomedical Knowledge Graph model that is phenotype and biological function-aware through integrating knowledge from multiple domains in a Neo4j, graph database. Allknown human genes were assessed through the ... -
Application of fundamental techniques for physicochemical characterizations to understand post-formulation performance of pharmaceutical nanocrystalline materials
(MPDI, 2021)Nanocrystalline materials (NCM, i.e., crystalline nanoparticles) have become an important class of materials with great potential for applications ranging from drug delivery and electronics to optics. Drug nanocrystals ... -
Application of multi‑method approach to assess groundwater–surface water interactions, for catchment management
(Springer, 2018)Globally, the dependence of river systems to delayed discharge of subsurface water to augment flows during dry seasons is well documented. Discharge of fresh subsurface water can dilute concentrated river flow quality ... -
Application of nano zinc oxide (nZnO) for the removal of triphenyltin chloride (TPT) from dockyard wastewater
(Water Research Commission, 2014)The use of triphenyltin chloride (TPT), a persistent organic pollutant, as a biocide has led to serious contamination of the marine environment. The potential of nano zinc oxide (nZnO) for the removal of TPT from contaminated ... -
Application of seismic stratigraphy in reservoir characterisation: A case study of the passive margin deposits of the northern Orange Basin, South Africa
(Springer Nature, 2020)The Barremian-Cenozoic depositional sequences in the northern Orange Basin, SW, South Africa, were investigated using the principles of seismic stratigraphy to understand the interplay of tectonics and sedimentary processes ... -
Application of surface-modified metal hydrides for hydrogen separation from gas mixtures containing carbon dioxide and monoxide
(Elsevier, 2013)Application of surface-modified MH material for H2 separation using temperature/pressure swing absorption–desorption was studied. The substrate alloy had the following composition LaNi3.55Co0.75Al0.4-Mn0.3, and the surface ... -
Application of the rainfall infiltration breakthrough (RIB) model for groundwater recharge estimation in west coastal South Africa
(Water Research Commission, 2013)Recharge estimation in arid and semi-arid areas is very challenging. The chloride mass balance method applied in western South Africa fails to provide reliable recharge estimates near coastal areas. A relationship between ... -
Application on gold nanoparticles-dotted 4-nitrophenylazo graphene in a label-free impedimetric deoxynivalenol immunosensor
(MDPI, 2015)In this paper, we report a new concept to construct a label-free electrochemical inhibition-based immunosensor for the detection of the mycotoxin deoxynivalenol (DON) in cereal samples. The electrochemical impedance ... -
Applications of Computational Methods in Biomedical Breast Cancer Imaging Diagnostics: A Review
(MDPI, 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ... -
Applications of computational methods in biomedical Breast cancer imaging diagnostics: A review
(MDPI, 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ... -
Applications of computational methods in biomedical breast cancer imaging diagnostics: A review
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ...