Browsing Faculty of Natural Sciences by Author "Enogieru, Adaze Bijou"
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Aqueous leaf extract of Sutherlandia frutescens attenuates ROS-induced apoptosis and loss of mitochondrial membrane potential in MPP+-treated SH-SY5Y cells
Ekpo, E. O.; Enogieru, Adaze Bijou; Omoruyi, Sylvester Ifeanyi (University of Benin, 2020)To investigate the neuroprotective activity of the aqueous extract of Sutherlandia frutescens (SF) against 1-methyl-4-phenylpyridinium (MPP+)-induced toxicity in SH-SY5Y neuroblastoma cells. Methods: SH-SY5Y neuroblastoma ... -
In vitro evaluation of the antiproliferative activity of Carpobrotus edulis on human neuroblastoma cells
Ekpo, Okobi Eko; Enogieru, Adaze Bijou; Omoruyi, Sylvester Ifeanyi (Elsivier, 2021)Neuroblastoma is a solid neuroendocrine tumour located outside the cranial cavity and contributes about 15% of all cancer‑associated deaths in children. Treatment of neuroblastoma is quite challenging and involves the use ... -
Rutin as a potent antioxidant: implications for neurodegenerative disorders
Enogieru, Adaze Bijou; Haylett, William; Hiss, Donavon Charles; Bardien, Soraya; Ekpo, Okobi Eko (Hindawi Publishing Corporation, 2018)A wide range of neurodegenerative diseases (NDs), including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and prion diseases, share common mechanisms such as neuronal loss, apoptosis, mitochondrial ...