Browsing Faculty of Natural Sciences by Subject "Drug design"
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DDESC: Dragon database for exploration of sodium channels in human
(BMC Cancer, 2008)Sodium channels are heteromultimeric, integral membrane proteins that belong to a superfamily of ion channels. The mutations in genes encoding for sodium channel proteins have been linked with several inherited genetic ... -
Potential broad spectrum inhibitors of the coronavirus 3CLpro: A virtual screening and structure-based drug design study
(MDPI, 2015)Human coronaviruses represent a significant disease burden; however, there is currently no antiviral strategy to combat infection. The outbreak of severe acute respiratory syndrome (SARS) in 2003 and Middle East respiratory ...