Browsing Faculty of Natural Sciences by Author "Ekpo, E. O."
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Aqueous leaf extract of Sutherlandia frutescens attenuates ROS-induced apoptosis and loss of mitochondrial membrane potential in MPP+-treated SH-SY5Y cells
Ekpo, E. O.; Enogieru, Adaze Bijou; Omoruyi, Sylvester Ifeanyi (University of Benin, 2020)To investigate the neuroprotective activity of the aqueous extract of Sutherlandia frutescens (SF) against 1-methyl-4-phenylpyridinium (MPP+)-induced toxicity in SH-SY5Y neuroblastoma cells. Methods: SH-SY5Y neuroblastoma ... -
An insight into the mechanism of holamine- and funtumine-induced cell death in cancer cells
Badmus, Jelili A.; Ekpo, E. O.; Sharma, Jyoti R. (MDPI, 2020)Holamine and funtumine, steroidal alkaloids with strong and diverse pharmacological activities are commonly found in the Apocynaceae family of Holarrhena. The selective anti-proliferative and cell cycle arrest effects of ...