Browsing Faculty of Natural Sciences by Author "van Helden, Paul D."
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Associations between human leukocyte antigen class I variants and the Mycobacterium tuberculosis subtypes causing disease
Salie, Muneeb; van der Merwe, Lize; Möller, Marlo; Daya, Michelle; van der Spuy, Gian D.; van Helden, Paul D.; Martin, Maureen P.; Gao, Xiao-jiang; Warren, Robin M.; Carrington, Mary; Hoal, Eileen G. (Oxford University Press, 2013)BACKGROUND. The development of active tuberculosis disease has been shown to be multifactorial. Interactions between host and bacterial genotype may influence disease outcome, with some studies indicating the adaptation ... -
A Panel of Ancestry Informative Markers for the Complex Five-Way Admixed South African Coloured Population
Daya, Michelle; van der Merwe, Lize; Galal, Ushma; Möller, Marlo; Salie, Muneeb; Chimusa, Emile R.; Galanter, Joshua M.; van Helden, Paul D.; Henn, Brenna M.; Gignoux, Chris R.; Hoal, Eileen G. (PloS, 2013)Admixture is a well known confounder in genetic association studies. If genome-wide data is not available, as would be the case for candidate gene studies, ancestry informative markers (AIMs) are required in order to adjust ...