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Evolution and structural analysis of Glossina morsitans (Diptera; Glossinidae) Tetraspanins
(MDPI, Basel, Switzerland, 2014)
Tetraspanins are important conserved integral membrane proteins expressed in
many organisms. Although there is limited knowledge about the full repertoire, evolution and structural characteristics of individual members ...
DDPC: Dragon database of genes associated with prostate cancer
(Oxford Journals, 2011)
Prostate cancer (PC) is one of the most commonly diagnosed cancers in men. PC is relatively difficult to diagnose due to a lack of clear early symptoms. Extensive research of PC has led to the availability of a large amount ...
Transcriptomic analysis reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain
(Plosone, 2008)
Our knowledge on zebrafish reproduction is very limited. We generated a gonad-derived cDNA microarray from zebrafish and used it to analyze large-scale gene expression profiles in adult gonads and other organs. We have ...
Inferring bona fide transfrags in RNA-Seq derived-transcriptome assemblies of non-model organisms
(BioMed Central, 2015)
Background: De novo transcriptome assembly of short transcribed fragments (transfrags) produced from sequencing-by-synthesis technologies often results in redundant datasets with differing levels of unassembled, partially ...
DDESC: Dragon database for exploration of sodium channels in human
(BMC Cancer, 2008)
Sodium channels are heteromultimeric, integral membrane proteins that belong to a superfamily of ion channels. The mutations in genes encoding for sodium channel proteins have been linked with several inherited genetic ...
Mice and men: Their promoter properties
(PLoS Genetics, 2006)
Using the two largest collections of Mus musculus and Homo sapiens transcription start sites (TSSs) determined based on CAGE tags, ditags, full-length cDNAs, and other transcript data, we describe the compositional landscape ...
DDEC: Dragon databaseof genes implicated in esophageal cancer
(BioMed Central, 2009)
Esophageal cancer ranks eighth in order of cancer occurrence. Its lethality primarily stems from inability to detect the disease during the early organ-confined stage and the lack of effective therapies for advanced-stage ...
Molecular evolution of key receptor genes in primates and non-human primates
(Science Publishing Group, 2014)
African primates remain an unexplored source of information required to complete the origin and evolution of many human pathogens. Current studies have shown the importance of several receptor human genes implicated in ...
A glance at quality score: implication for de novo transcriptome reconstruction of Illumina reads
(Frontiers, 2014)
Downstream analyses of short-reads from next-generation sequencing platforms are often preceded by a pre-processing step that removes uncalled and wrongly called bases. Standard approaches rely on their associated base ...
Genome-wide SNP identification by high-throughput sequencing and selective mapping allows sequence assembly positioning using a framework genetic linkage map
(BioMed Central, 2010)
Determining the position and order of contigs and scaffolds from a genome assembly within an organism’s genome remains a technical challenge in a majority of sequencing projects. In order to exploit contemporary technologies ...