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Desalination and seawater quality at Green Point, Cape Town: A study on the effects of marine sewage outfalls
(Academy of Science of South Africa (ASSAf), 2017)
This paper presents our collection methods, laboratory protocols and findings in respect of sewage pollution
affecting seawater and marine organisms in Table Bay, Cape Town, South Africa, then moves to consider ...
Occurrences, levels and risk assessment studies of emergingpollutants (pharmaceuticals, perfluoroalkyl and endocrine disruptingcompounds) infish samples from Kalk Bay harbour, South Africa
(Elsevier, 2019)
A comprehensive analysis of 15 target chemical compounds (pharmaceuticals and personal care product,perfluoroalkyl compounds and industrial chemicals) were carried out to determine their concentrationsin selected commercially ...
Regulatory registration timelines of generic medicines in South Africa: Assessment of the performance of SAHPRA between 2011 and 2022
(Springer, 2023)
Various regulatory authorities are experiencing backlogs of applications which result in delayed access
to medicines for patients. The objective of this study is to critically assess the registration process utilised by ...
Contaminants of emerging concern (cecs) and male reproductive health: Challenging the future with a double-edged sword
(MDPI, 2023)
Approximately 9% of couples are infertile, with half of these cases relating to male factors.
While many cases of male infertility are associated with genetic and lifestyle factors, approximately
30% of cases are still ...
Zinc(ii) complex of (z)-4-((4-nitrophenyl)amino)pent-3-en-2-one, a potential antimicrobial agent: Synthesis, characterization, antimicrobial screening, dft calculation and docking study
(Chemical Society of Ethiopia, 2023)
Herein, the synthesis and characterizations of (Z)-4-((4-nitrophenyl)amino)pent-3-en-2-one (HL) ligand and its Zn(II) complex are reported. The compounds were characterized using elemental and thermogravimetric (TGA) ...
Quantum dot nanotoxicity investigations using human lung cells and toxor electrochemical enzyme assay methodology
(American Chemical Society, 2017)
Recent studies have suggested that certain
nanomaterials can interfere with optically based cytotoxicity
assays resulting in underestimations of nanomaterial toxicity. As
a result there has been growing interest in the ...
Documentation of antipsychotic-related adverse drug reactions: An educational intervention
(AOSIS, 2019)
Antipsychotic agents are associated with harmful adverse reactions which
impact negatively on patient adherence and clinical management. Accurate and complete
documentation of signs and symptoms in the clinical notes is ...
Synthesis of ester-linked ursolic acid-based hybrid compounds: Potential antibacterial and anticancer agents
(Wiley, 2023)
The molecular hybridization of two or more drugs into a single molecule is an effective drug design approach
to reduce pill burden and improve patient treatment adherence. Ursolic acid-based hybrid compounds were
synthesized ...
Tandem lc-ms identification of antitubercular compounds in zones of growth inhibition produced by South African filamentous actinobacteria
(MDPI, 2023)
Novel antitubercular compounds are urgently needed to combat drug-resistant Mycobacterium
tuberculosis (Mtb). Filamentous actinobacteria have historically been an excellent source of
antitubercular drugs. Despite this, ...
Preparation and evaluation of pralidoxime-loaded plga nanoparticles as potential carriers of the drug across the blood brain barrier
(Hindawi, 2015)
Pralidoxime is an organophosphate antidote with poor central nervous system distribution due to a high polarity. In the present
study, pralidoxime-loaded poly(lactic-co-glycolic acid) nanoparticles were prepared and ...