Browsing Research Articles (Biotechnology) by Subject "Hypertension"
Now showing items 1-6 of 6
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The association of mthfr (rs1801133) with hypertension in an indigenous South African population
(Frontiers Media, 2022)The current study sought to investigate the association between the methylenetetrahydrofolate reductase (MTHFR) variant (rs1801133) and the risk of developing hypertension (HTN) in an indigenous South African population.A ... -
Cross-sectional study of the association of 5 single nucleotide polymorphisms with enalapril treatment response among South African adults with hypertension
(NLM (Medline), 2021-11-19)This study investigates the association of 5 single nucleotide polymorphisms (SNPs) in selected genes (ABO, VEGFA, BDKRB2, NOS3, and ADRB2) with blood pressure (BP) response to enalapril. The study further assessed genetic ... -
Hypertension in African populations: Review and computational insights
(MPDI, 2021)Hypertension (HTN) is a persistent public health problem affecting approximately 1.3 billion individuals globally. Treatment-resistant hypertension (TRH) is defined as high blood pressure (BP) in a hypertensive patient ... -
Methylenetetrahydrofolate Reductase Polymorphism (rs1801133) and the Risk of Hypertension among African Populations: A Narrative Synthesis of Literature
(MDPI, 2022)In this review, we have gathered and analyzed the available genetic evidence on the association between the methylenetetrahydrofolate reductase gene (MTHFR), rs1801133 and the risk of Hypertension (HTN) in African ... -
Single nucleotide polymorphisms in amlodipine-associated genes and their correlation with blood pressure control among South African adults with hypertension
(MDPI, 2022)This study describes the single nucleotide polymorphisms (SNPs) in amlodipineassociated genes and assesses their correlation with blood pressure control among South African adults with hypertension. Methods: In total, ... -
Socio-demographic and modifiable risk factors of diabetes and hypertension among resource constrained patients from rural areas in mdantsane township in South Africa
(Makerere University, 2020)Recently, developing countries have shown a dramatic increase in non-communicable diseases (NCDs). The burden of NCDs in South Africa has increased over the past years resulting in an estimated 37% of all-cause mortality ...