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    DAMPD: a manually curated antimicrobial peptide database 

    Sundararajan, Vijayaraghava S.; Gabere, Musa N.; Pretorius, Ashley; Adam, Saleem; Christoffels, Alan; Minna, Lehvaslaiho; Archer, John A.C.; Bajic, Vladimir B. (Oxford University Press, 2012)
    The demand for antimicrobial peptides (AMPs) is rising because of the increased occurrence of pathogens that are tolerant or resistant to conventional antibiotics. Since naturally occurring AMPs could serve as templates ...
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    The African Coelecanth genome provides insights into tetrapod evolution 

    Christoffels, Alan; Hesse, Uljana; Gamieldien, Junaid; Panji, Sumir; Picone, Barbara; Van Heusden, Peter (Macmillan Publishers, 2013)
    The discovery of a living coelacanth specimen in 1938 was remarkable, as this lineage of lobe-finned fish was thought to have become extinct 70 million years ago. The modern coelacanth looks remarkably similar to many of ...
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    Gonad differentiation in zebrafish is regulated by the canonical Wnt signalling pathway 

    Sreenivasan, Rajini; Jiang, Junhai; Wang, Xingang; Bartfai, Richard; Kwan, Hsiao, Y.; Christoffels, Alan; Orban, Laszlo (Society for the Study of Reproduction, 2014)
    Zebrafish males undergo a ‘‘juvenile ovary-to-testis’’ gonadal transformation process. Several genes, including nuclear receptor subfamily 5, group A (nr5a) and anti-Mu¨ llerian hormone (amh), and pathways such as Tp53-mediated ...
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    DDPC: Dragon database of genes associated with prostate cancer 

    Maqungo, Monique; Kaur, Mandeep; Kwofie, Samuel K.; Radovanovic, Aleksander; Schaefer, Ulf; Schmeier, Sebastian; Oppon, Ekow; Christoffels, Alan; Bajic, Vladimir B. (Oxford Journals, 2011)
    Prostate cancer (PC) is one of the most commonly diagnosed cancers in men. PC is relatively difficult to diagnose due to a lack of clear early symptoms. Extensive research of PC has led to the availability of a large amount ...
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    Transcriptomic analysis reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain 

    Sreenivasan, Rajini; Cai, Minnie; Bartfai, Richard; Wang, Xingang; Orban, Laszlo; Christoffels, Alan (Plosone, 2008)
    Our knowledge on zebrafish reproduction is very limited. We generated a gonad-derived cDNA microarray from zebrafish and used it to analyze large-scale gene expression profiles in adult gonads and other organs. We have ...
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    Inferring bona fide transfrags in RNA-Seq derived-transcriptome assemblies of non-model organisms 

    Mbandi, Stanley K.; Hesse, Uljana; Van Heusden, Peter; Christoffels, Alan (BioMed Central, 2015)
    Background: De novo transcriptome assembly of short transcribed fragments (transfrags) produced from sequencing-by-synthesis technologies often results in redundant datasets with differing levels of unassembled, partially ...
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    Mice and men: Their promoter properties 

    Bajic, Vladimir B.; Tan, Sin lam; Christoffels, Alan; Schonbach, Christian; Lipovich, Leonard; Yang, Liang; Hofmann, Oliver; Kruger, Adele; Hide, Winston; Kai, Chikatoshi; Kawai, Jun; Hume, David, A.; Carninci, Piero; Hayashizaki, Yoshihide (PLoS Genetics, 2006)
    Using the two largest collections of Mus musculus and Homo sapiens transcription start sites (TSSs) determined based on CAGE tags, ditags, full-length cDNAs, and other transcript data, we describe the compositional landscape ...
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    DDEC: Dragon databaseof genes implicated in esophageal cancer 

    Essack, Magbubah; Radovanovic, Aleksander; Schaefer, Ulf; Schmeier, Sebastian; Seshadri, Sundararajan V.; Christoffels, Alan; Kaur, Mandeep; Bajic, Vladimir B. (BioMed Central, 2009)
    Esophageal cancer ranks eighth in order of cancer occurrence. Its lethality primarily stems from inability to detect the disease during the early organ-confined stage and the lack of effective therapies for advanced-stage ...
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    DDESC: Dragon database for exploration of sodium channels in human 

    Sagar, Sunil; Kaur, Mandeep; Dawe, Adam; Seshadri, Sundararajan V.; Christoffels, Alan; Schaefer, Ulf; Radovanovic, Aleksander; Bajic, Vladimir B. (BMC Cancer, 2008)
    Sodium channels are heteromultimeric, integral membrane proteins that belong to a superfamily of ion channels. The mutations in genes encoding for sodium channel proteins have been linked with several inherited genetic ...
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    Database for exploration of functional context of genes implicated in ovarian cancer 

    Kaur, Mandeer; Radovanovic, Aleksander; Essack, Magbubah; Schaefer, Ulf; Maqungo, Monique; Kibler, Tracey; Schmeier, Sebastian; Christoffels, Alan; Narasimhan, Kothandaraman; Choolani, Mahesh; Bajic, Vladimir B. (Oxford Journals, 2009)
    Ovarian cancer (OC) is becoming the most common gynecological cancer in developed countries and the most lethal gynecological malignancy. It is also the fifth leading cause of all cancer-related deaths in women. The ...
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    Christoffels, Alan (29)
    Bajic, Vladimir B. (6)Van Heusden, Peter (5)Hesse, Uljana (4)Radovanovic, Aleksander (4)Schaefer, Ulf (4)Bartfai, Richard (3)Kaur, Mandeep (3)Masiga, Daniel K. (3)Mbandi, Stanley K. (3)... View MoreSubjectGenome sequencing (3)Reproduction (3)Zebrafish (3)Database (2)Drosophila melanogaster (2)Glossina morsitans (2)Mycobacterium tuberculosis (2)Sleeping sickness (2)Transcriptome reconstruction (2)Tsetse fly (2)... View MoreDate Issued2010 - 2019 (23)2004 - 2009 (6)

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