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Whole-genome sequencing of African swine fever virus from wild boars in the Kaliningrad region reveals unique and distinguishing genomic mutations
(Frontiers Media, 2023)
Since the first report of outbreaks of African swine fever (ASF)
in Georgia in 2007, the disease has expanded into Europe, Russia, and Asia,
spreading rapidly via contact with infected animals including domestic pigs
and ...
Plausible explanation for the third COVID-19 wave in India and its implications
(KeAi Communications, 2023)
Recently some of us used a random-walk Monte Carlo simulation approach to study the spread of COVID-19. The calculations were reasonably successful in describing secondary and tertiary waves of infection, in countries such ...
Human coronavirus OC43 3CL protease and the potential of ML188 as a broad-spectrum lead compound: Homology modelling and molecular dynamic studies
(Springer Nature, 2015)
The coronavirus 3 chymotrypsin-like protease (3CLpro) is a validated target in the design of potential
anticoronavirus inhibitors. The high degree of homology within the protease’s active site and substrate conservation
supports ...
Human coronavirus research: 20 years since the SARS-CoV outbreak
(Frontiers Media, 2022)
This Editorial introduces 10 articles published in a Special Issue highlighting human
coronavirus (hCoV) research on the twentieth anniversary of the outbreak of severe
acute respiratory syndrome (SARS) in late 2002. ...
Computational insight of dexamethasone against potential targets of SARS-CoV-2
(Taylor and Francis Group, 2022)
The health sector has been on the race to find a potent therapy for coronavirus disease (COVID)-19, a
diseases caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2. Repurposed anti-viral
drugs have played ...
Modelling human protein interaction networks as metric spaces has potential in disease research and drug target discovery
(BMC, 2014)
We have recently shown by formally modelling human protein interaction networks (PINs) as metric
spaces and classified proteins into zones based on their distance from the topological centre that hub proteins are
primarily ...
Functional prediction of candidate micrornas for CRC management using in silico approach
(MDPI, 2019)
Approximately 30–50% of malignant growths can be prevented by avoiding risk factors
and implementing evidence-based strategies. Colorectal cancer (CRC) accounted for the second most
common cancer and the third most common ...
Is human immunodeficiency virus (HIV) stage an independent risk factor for altering the periodontal status of HIV-positive patients? A South African study
(BMC, 2013)
The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The
aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could
independently be associated ...
Modeling the impact of combined use of Covid Alert SA app and vaccination to curb Covid-19 infections in South Africa
(Public Library of Science, 2023)
The unanticipated continued deep-rooted trend of the Severe Acute Respiratory Syndrome
Corona-virus-2 the originator pathogen of the COVID-19 persists posing concurrent anxiety
globally. More effort is affixed in the ...
Control and elimination in an SEIR model for the disease dynamics of Covid-19 with vaccination
(AIMS Press, 2023)
COVID-19 has become a serious pandemic affecting many countries around the world
since it was discovered in 2019. In this research, we present a compartmental model in ordinary
differential equations for COVID-19 with ...