Search
Now showing items 51-60 of 60
Variant-specific introduction and dispersal dynamics of SARS-CoV-2 in New York City – from Alpha to Omicron
(Public Library of Science, 2023)
Since the latter part of 2020, SARS-CoV-2 evolution has been characterised by the emergence of viral variants associated with distinct biological characteristics. While the main
research focus has centred on the ability ...
Situation analysis on the regulation of nanomedicines in Southern Africa
(Frontiers Media, 2023)
Medical products incorporating nanoparticle drug delivery
systems (nanomedicines) are therapeutic or imaging agents, which comprise
a delivery system within the nanometer size range (1 – 1000 nm). As medical
products, ...
The validation of a simple, robust, stability-indicating rp-hplc method for the simultaneous detection of lamivudine, tenofovir disoproxil fumarate, and dolutegravir sodium in bulk material and pharmaceutical formulations
(Hindawi, 2022)
An effective analytical method is requisite to ensure the accurate identification and quantification of drug(s), either in bulk
material or in complex matrices, which form part of finished pharmaceutical products. For the ...
Causes and patterns of morbidity and mortality in Afghanistan: Joint estimation of multiple causes in the neonatal period
(Springer, 2014)
This paper focuses on investigating the leading cause(s) of death and preventable factors in Afghanistan,
using data from verbal autopsies of infant deaths. We are of the view that the presence
of a disease in a person ...
Modeling the impact of combined use of Covid Alert SA app and vaccination to curb Covid-19 infections in South Africa
(Public Library of Science, 2023)
The unanticipated continued deep-rooted trend of the Severe Acute Respiratory Syndrome
Corona-virus-2 the originator pathogen of the COVID-19 persists posing concurrent anxiety
globally. More effort is affixed in the ...
A synthesis review of vitamins involved in the fight against Covid-19
(Wiley, 2022)
Although literature studies on earlier viruses such as
the Severe Acute Respiratory Syndrome (SARS), the
Middle East Respiratory Syndrome (MERS), and
other similar viruses, in terms of treatment of coronavirus
suggested ...
Whole-genome sequencing of African swine fever virus from wild boars in the Kaliningrad region reveals unique and distinguishing genomic mutations
(Frontiers Media, 2023)
Since the first report of outbreaks of African swine fever (ASF)
in Georgia in 2007, the disease has expanded into Europe, Russia, and Asia,
spreading rapidly via contact with infected animals including domestic pigs
and ...
Tandem lc-ms identification of antitubercular compounds in zones of growth inhibition produced by South African filamentous actinobacteria
(MDPI, 2023)
Novel antitubercular compounds are urgently needed to combat drug-resistant Mycobacterium
tuberculosis (Mtb). Filamentous actinobacteria have historically been an excellent source of
antitubercular drugs. Despite this, ...
Inhibition of HIV-1 enzymes, antioxidant and anti-inflammatory activities of Plectranthus barbatus
(Elsevier, 213)
Ethnopharmacological relevance: Plectranthus barbatus is widely used in African countries as an herbal
remedy to manage HIV/AIDS and related conditions.
Aim of the study: To investigate the HIV-1 inhibitory, anti-inflammatory ...
Covid-19 among adults living with HIV: Correlates of mortality among public sector healthcare users in Western Cape, South Africa
(Wiley, 2023)
Introduction: While a large proportion of people with HIV (PWH) have experienced SARS-CoV-2 infections, there is uncertainty
about the role of HIV disease severity on COVID-19 outcomes, especially in lower-income settings. ...