Browsing Research Articles (Biotechnology) by Title
Now showing items 176-195 of 219
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Proteomic identification and meta-analysis in salvia hispanica RNA-seq de novo assemblies
(2021)While proteomics has demonstrated its value for model organisms and for organisms with mature genome sequence annotations, proteomics has been of less value in nonmodel organisms that are unaccompanied by genome sequence ... -
PZQ Therapy: How close are we in the development of effective alternative anti-schistosomal drugs?
(Bentham Science Publishers, 2019)Today schistosomiasis, caused mainly by the three major schistosome species (S. mansoni, S. haematobium and S. japonicum), has for many decades and still continues to be on a rapid and swift rise globally, claiming ... -
Recent advancements in the breeding of sorghum crop: current status and future strategies for marker-assisted breeding
(Frontiers, 2023)Sorghum is emerging as a model crop for functional genetics and genomics of tropical grasses with abundant uses, including food, feed, and fuel, among others. It is currently the fifth most significant primary cereal crop. ... -
The Relationship between Cadmium Toxicity and the Modulation of Epigenetic Traits in Plants
(International Journal of Molecular Sciences, 2021-06)Elevated concentrations of heavy metals such as cadmium (Cd) have a negative impact on staple crop production due to their ability to elicit cytotoxic and genotoxic effects on plants. In order to understand the relationship ... -
Reports of plant-derived nanoparticles for prostate cancer therapy
(MDPI, 2023)Plants have demonstrated potential in providing various types of phytomedicines with chemopreventive properties that can combat prostate cancer. However, despite their promising in vitro activity, the incorporation of these ... -
Reports of plant-derived nanoparticles for prostate cancer therapy
(MDPI, 2023)Plants have demonstrated potential in providing various types of phytomedicines with chemopreventive properties that can combat prostate cancer. However, despite their promising in vitro activity, the incorporation of ... -
Reports of Plant-Derived Nanoparticles for Prostate Cancer Therapy
(Plants, 2023)Background: Plants have demonstrated potential in providing various types of phytomedicines with chemopreventive properties that can combat prostate cancer. However, despite their promising in vitro activity, the incorporation ... -
Response of soybean nodules to exogenously applied caffeic acid during NaCl-induced salinity
(Elsevier, 2015)affeic acid acts as an antioxidant to scavenge reactive oxygen species, but its influence on plant responses to abi- otic stresses is only partially understood. Here, we investigated the influence of exogenously applied ... -
Role and merits of green based nanocarriers in cancer treatment
(MPDI, 2021)The use of nanocarriers for biomedical applications has been gaining interests from researchers worldwide for the delivery of therapeutics in a controlled manner. These “smart” vehicles enhance the dissolution and the ... -
The Role of Cytoskeletal Proteins in the Formation of a Functional In Vitro Blood-Brain Barrier Model
(MDPI, 2022)The brain capillary endothelium is highly regulatory, maintaining the chemical stability of the brain’s microenvironment. The role of cytoskeletal proteins in tethering nanotubules (TENTs) during barrier-genesis was ... -
Rooibos (Aspalathus linearis) genome size estimation using flow cytometry and k-mer analyses
(MDPI, 2020)Plant genomes provide information on biosynthetic pathways involved in the production of industrially relevant compounds. Genome size estimates are essential for the initiation of genome projects. The genome size of rooibos ... -
Seed germination and seedling establishment in pistacia atlantica desf. and pistacia lentiscus l. under drought
(Russian Journal of Plant Physiology, 2023)The rehabilitation of degraded Mediterranean areas requires reintroduction of key-stone woody species. However, seed germination and seedling establishment for native species are poor. Germination behavior of Pistacia ... -
Seed priming with MeJa prevents salt-induced growth inhibition and oxidative damage in sorghum bicolor by inducing the expression of jasmonic acid biosynthesis genes
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Salinity is one of the major detrimental abiotic stresses at the forefront of deterring crop productivity globally. Although the exogenous application of phytohormones has formerly proven efficacious to plants, their effect ... -
A simple, high-throughput modeling approach reveals insights into the mechanism of gametophytic self-incompatibility
(Nature Research, 2016)Specificity in the GSI response results from the S-haplotype-specific molecular interaction of S-locus F-box (SLF/SFB) and SRNase proteins in the self-incompatibility locus (S-locus). The answer to the question of how ... -
Single nucleotide polymorphisms associated with metformin and sulphonylureas’ glycaemic response among South African adults with type 2 diabetes mellitus
(MDPI, 2021)To examine the association of polymorphisms belonging to SLC22A1, SP1, PRPF31, NBEA, SCNN1B, CPA6 and CAPN10 genes with glycaemic response to metformin and sulphonylureas (SU) combination therapy among South African adults ... -
Single nucleotide polymorphisms in amlodipine-associated genes and their correlation with blood pressure control among South African adults with hypertension
(MDPI, 2022)This study describes the single nucleotide polymorphisms (SNPs) in amlodipineassociated genes and assesses their correlation with blood pressure control among South African adults with hypertension. Methods: In total, ... -
Socio-demographic and modifiable risk factors of diabetes and hypertension among resource constrained patients from rural areas in mdantsane township in South Africa
(Makerere University, 2020)Recently, developing countries have shown a dramatic increase in non-communicable diseases (NCDs). The burden of NCDs in South Africa has increased over the past years resulting in an estimated 37% of all-cause mortality ... -
Stress modulation as a means to improve yeasts for lignocellulose bioconversion
(Springer, 2021)The second-generation (2G) fermentation environment for lignocellulose conversion presents unique challenges to the fermentative organism that do not necessarily exist in other industrial fermentations. While extreme ... -
Structural analysis, molecular modelling and preliminary competition binding studies of AM-DAN as a NMDA receptor PCP-Site fluorescent ligand
(MDPI, 2019): Excitotoxicity related to the dysfunction of the N-methyl-d-aspartate receptor (NMDAR) has been indicated to play an integral role in the pathophysiology of multiple disease states, including neurodegenerative disorders ... -
Structure and biosynthesis of carotenoids produced by a novel Planococcus sp. isolated from South Africa
(BMC, 2022)The genus Planococcus is comprised of halophilic bacteria generally reported for the production of carotenoid pigments and biosurfactants. In previous work, we showed that the culturing of the orange-pigmented Planococcus ...