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Cross-sectional study of the association of 5 single nucleotide polymorphisms with enalapril treatment response among South African adults with hypertension
(NLM (Medline), 2021-11-19)
This study investigates the association of 5 single nucleotide polymorphisms (SNPs) in selected genes (ABO, VEGFA, BDKRB2, NOS3, and ADRB2) with blood pressure (BP) response to enalapril. The study further assessed genetic ...
Glucose-uptake activity and cytotoxicity of diterpenes and triterpenes isolated from lamiaceae plant species
(2020)
The prevalence of diabetes mellitus (DM), considered one of the most common metabolic disorders, has dramatically increased and resulted in higher rates of morbidity and mortality around the world in the past decade. It ...
The potential of chalcone-capped gold nanoparticles for the management of diabetes mellitus
(Surfaces and Interfaces, 2021-08)
Searching for new natural bioactive capping agents represent an urgent priority in the green synthesis of metal nanoparticles. Additionaly, the biosaftey of metal nanparticles is a major concern especially in medical ...
Prevalence, patterns and determinants of dyslipidaemia among South African adults with comorbidities
(Nature Research, 2022)
The present study assessed the prevalence, patterns and determinants of dyslipidaemia among South African adults with multi-morbidities. In this study, 614 individuals with DM and hypertension were recruited. Dyslipidaemia ...
Single nucleotide polymorphisms in amlodipine-associated genes and their correlation with blood pressure control among South African adults with hypertension
(MDPI, 2022)
This study describes the single nucleotide polymorphisms (SNPs) in amlodipineassociated
genes and assesses their correlation with blood pressure control among South African
adults with hypertension. Methods: In total, ...
Development of infectious transcripts and genome manipulation of black queen-cell virus of honey bees
(Microbiology Society, 2002)
The South African isolate of Black queen-cell virus (BQCV), a honey bee virus, was previously found
to have an 8550 nucleotide genome excluding the poly(A) tail. Its genome contained two ORFs, a
5«-proximal ORF encoding ...
Genetic preservation of SLC22A3 in the Admixed and Xhosa populations living in the Western Cape
(Springer Science and Business Media B.V., 2023)
Background Amphiphilic solute facilitator organic cation transporters mediate the movement of various endogenous and
exogenous organic cations, including crucial drugs like metformin, oxaliplatin, and lamivudine. These ...