Browsing Medical Bioscience by Title
Now showing items 165-184 of 277
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Medicinal properties and in vitro biological activities of selected helichrysum species from South Africa: A review
(MDPI, 2021)The genus Helichrysum Mill comprises hundreds of species that are mostly flowering perennial shrubs. Some of these plants that belong to the Helichrysum species are used in traditional medicine to treat cough, back pain, ... -
MERS-CoV: Understanding the latest human coronavirus threat
(MDPI, 2018)Human coronaviruses cause both upper and lower respiratory tract infections in humans. In 2012, a sixth human coronavirus (hCoV) was isolated from a patient presenting with severe respiratory illness. The 60-year-old man ... -
Metronidazole in the Prophylaxis and treatment of Anaerobic Infection
(Health and Medical Publishing Group, 1978)The influence of prophylactic metronidazole on vaginal carriage rates of anaerobes and the development of postoperative anaerobic infection was studied in 104 women who underwent abdominal hysterectomy. Metronidazole ... -
The Microbial Aetiology of Periodontal Diseases
(InTech, 2012)Introduction: The study of the aetiology of periodontal diseases has continued for decades with much progress shown in the last two decades. Having moved through periods of “whole” plaque (with emphasis on mass) being ... -
Microplastic sources, formation, toxicity and remediation: A review
(Springer, 2023)Microplastic pollution is becoming a major issue for human health due to the recent discovery of microplastics in most ecosystems. Here, we review the sources, formation, occurrence, toxicity and remediation methods of ... -
Microstructurally-based constitutive modelling of the skin – Linking intrinsic ageing to microstructural parameters
(Elsevier, 2018)A multiphasic constitutive model of the skin that implicitly accounts for the process of intrinsic (i.e. chronological) ageing via variation of the constitutive parameters is proposed. The structurally-motivated constitutive ... -
Microtubular dysfunction and male infertility
(Korean Society for Sexual Medicine and Andrology, 2018)Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain ... -
Molecular detection of tick-borne pathogen diversities in ticks from livestock and reptiles along the shores and adjacent islands of lake Victoria and lake Baringo, Kenya
(Frontiers Media, 2017)Tick-borne pathogens (TBPs) are responsible for some of the most serious emerging infectious diseases facing sub-Saharan Africa (SSA) and the rest of the world today (1, 2). In Kenya, TBPs (including viral diseases—arboviruses) ... -
Molecular genetic identification of skeletal remains of apartheid activists in South Africa
(Academic Journals, 2008)The Truth and Reconciliation Commission made significant progress in examining abuses committed during the apartheid era in South Africa. Despite information revealed by the commission, a large number of individuals ... -
Monoclonal Antibodies targeting the HR2 Domain and the region immediately upstream of the HR2 of the S Protein neutralize in Vitro Infection of Severe Acute Respiratory Syndrome Coronavirus
(American Society for Microbiology, 2006)We have previously shown that an Escherichia coli-expressed, denatured spike (S) protein fragment of the severe acute respiratory coronavirus, containing residues 1029 to 1192 which include the heptad repeat 2 (HR2) ... -
Morphological and physiological responses of Calobota sericea plants subjected to water limitation and subsequent rewatering
(Taylor and Francis Group, 2021)Calobota sericea is a native legume of South Africa, confined to the water-limited rangelands, and it has recently been prioritised for additional characterisation regarding its pasture potential. In this study, we examined ... -
Morphometric and structural analysis of Florida manateespermatozoa
(Wiley, 2022)Sperm characteristics, such as sperm morphology and sperm morphometry areimportant in assessing sperm quality. This is especially important for the man-agement and conservation of endangered and exotic species, like the ... -
Multi-drug resistant (MDR) oral Candida species isolated from HIV-positive patients in South Africa and Cameroon
(Elsevier, 2014)Candida species are a common cause of infection in immune-compromised HIV-positive individuals, who are usually treated with the antifungal drug, fluconazole in public hospitals in Africa. However, information about the ... -
Muscle fiber type and metabolic profiles of four muscles from the African black ostrich
(Meat Science, 2023)Muscle fiber type, fiber cross-sectional area (CSA), enzyme activities (citrate synthase (CS), 3-hydroxyacetyl Co A dehydrogenase (3HAD), lactate dehydrogenase (LDH) and phosphofructokinase (PFK)) and glycogen content were ... -
The new 6th edition of the WHO laboratory manual for the examination and processing of human semen: Is it a step toward better standard operating procedure?
(Shanghai Institute Materia Medica, 2021)Semen analysis (SA) remains the cornerstone of male infertility evaluation and should ideally be performed by an accredited andrology laboratory or in vitro fertilization (IVF) clinics based on the standards defined ... -
Next generation precision medicine: Crispr-mediated genome editing for the treatment of neurodegenerative disorders
(Springerlink, 2019)Despite significant advancements in the field of molecular neurobiology especially neuroinflammation and neurodegeneration, the highly complex molecular mechanisms underlying neurodegenerative diseases remain elusive. As ... -
The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein
(Elsevier, 2007)Severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) caused a severe outbreak in several regions of the world in 2003. The SARS-CoV genome is predicted to contain 14 functional open reading frames (ORFs). The ... -
Novel additive for sperm cryopreservation media: Holotheria parva coelomic cavity extract protects human spermatozoa against oxidative stress—A pilot study
(Wiley-Blackwell, 2020)Cryopreservation is the most effective method for preserving semen for a long period of time. However, during the freeze–thaw process, production of reactive oxygen species (ROS) leads to a steep reduction in sperm fertility ... -
A novel cell-based binding assay system reconstituting interaction between SARS-CoV S protein and its cellular receptor
(Elsevier, 2005)Severe acute respiratory syndrome (SARS), a life-threatening disease, is caused by the newly identified virus SARS coronavirus (SARSCoV). In order to study the spike (S) protein of this highly contagious virus, we established ... -
A Novel Severe Acute Respiratory Syndrome Coronavirus Protein, U274, is transported to the Cell Surface and undergoes Endocytosis
(American Society for Microbiology, 2004)The severe acute respiratory syndrome coronavirus (SARS-CoV) genome contains open reading frames (ORFs) that encode for several genes that are homologous to proteins found in all known coronaviruses. These are the replicase ...