Browsing Medical Bioscience by Issue Date
Now showing items 181-200 of 277
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The validity and reliability of computer-aided semen analyzers in performing semen analysis: a systematic review
(Translational Andrology and Urology., 2021)Background: Computer-aided sperm analyzers (CASA) are currently used worldwide for semen analysis. However, there are doubts about their reliability to fully substitute the human operator. Therefore, this study aimed to ... -
A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility
(The world journal of men's health, 2021)Globally, infertility impacts 15% of couples trying to conceive. The incidence of male infertility has been increasing over the past several decades, ranging from 20% to 70% worldwide [1,2]. The male partner is found to ... -
Comparative analysis of the constitution and implementation of race/skin color field in health information systems: Brazil and South Africa
(Spinger, 2021)The inclusion of race/skin color in Health Information Systems makes it possible to measure health inequities. Brazil and South Africa correspond to countries marked by profound inequalities, multiracial constituted that ... -
The impact of COVID-19 on the male reproductive tract and fertility: A systematic review
(Informa UK Limited, trading as Taylor & FrancisGroup., 2021)Objective: The COVID-19 pandemic, caused by the acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), remains an ongoing public health challenge. Although males are affected slightly more than females, the impact of ... -
Alternative medicine and herbal remedies in the treatment of erectile dysfunction: A systematic review
(Informa UK Limited, trading as Taylor & Francis Group., 2021)Objectives: To systematically review and discuss the current evidence from placebo-controlled clinical trials that investigated the use of alternative medicines and herbal remedies in the management of erectile dysfunction ... -
Aqueous leaf extract of Moringa oleifera reduced intracellular ROS production, DNA fragmentation and acrosome reaction in Human spermatozoa in vitro
(Blackwell Publishing Ltd, 2021)The effects of aqueous leaf extract of Moringa oleifera (MO) on human sperm functions and integrity was studied in vitro. Semen was obtained by masturbation after 3–5 days' abstinence from 34 healthy donors in Western Cape, ... -
Epididymal contribution to male infertility: An overlooked problem
(Blackwell Publishing Ltd, 2021)The diagnosis and treatment of male infertility, excluding assisted conception, are limited because of, but not limited to, poor understanding of sperm post-testicular development and storage. Many may think that sperm ... -
Medicinal properties and in vitro biological activities of selected helichrysum species from South Africa: A review
(MDPI, 2021)The genus Helichrysum Mill comprises hundreds of species that are mostly flowering perennial shrubs. Some of these plants that belong to the Helichrysum species are used in traditional medicine to treat cough, back pain, ... -
Chemical composition and cosmeceutical potential of the essential oil of oncosiphon suffruticosum (L.) Källersjö
(MDPI, 2021)The South African medicinal plant Oncosiphon suffruticosum (L.) Källersjö is an important remedy used to treat chronic, respiratory, and skin ailments. From the essential oil (EO) extracted by the hydrodistillation, ... -
Records of ctenophores from South Africa
(PeerJ Inc., 2021)Although ctenophores can be conspicuous components of the plankton in coastal marine ecosystems, only six species have been formally described from around South Africa. Using photographs from local community scientists, ... -
Male infertility
(Lancet Publishing Group, 2021)It is estimated that infertility affects 8–12% of couples globally, with a male factor being a primary or contributing cause in approximately 50% of couples. Causes of male subfertility vary highly, but can be related to ... -
Comparative analysis of tests used to assess sperm chromatin integrity and DNA fragmentation
(Blackwell Publishing Ltd, 2021)Male infertility has a complex etiology, and many times, the cause is unknown. While routine semen analysis provides an overview of basic semen parameters, such as sperm concentration, motility, viability and morphology, ... -
TUNEL assay—Standardized method for testing sperm DNA fragmentation
(Blackwell Publishing Ltd, 2021)Sperm DNA integrity is important for normal functions such as fertilization, implantation, pregnancy and fetal development. Sperm DNA fragmentation (SDF) is more common in infertile men and may be responsible for poor ... -
Association of XRCC1 and ERCC2 promoters’ methylation with chromatin condensation and sperm DNA fragmentation in idiopathic oligoasthenoteratozoospermic men
(Blackwell Publishing Ltd, 2021)The aim of the study was to investigate whether the promoter methylation of XRCC1 and ERCC2 genes is associated with sperm DNA fragmentation and chromatin condensation in idiopathic oligoasthenoteratozoospermic men. This ... -
Evaluation of seminal oxidation–reduction potential in male infertility
(Blackwell Publishing Ltd, 2021)The role of oxidative stress in male infertility has been broadly recognised, and the search for a new marker to determine the redox environment in semen has gained considerable interest. Oxidation–reduction potential (ORP) ... -
Reactive oxygen species in male reproduction: A boon or a bane?
(Blackwell Publishing Ltd, 2021)Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ... -
In vitro comparison of the anti-proliferative effects of galenia africana on human skin cell lines
(MDPI, 2021)Malignant melanoma is the major cause of skin cancer-related deaths. Surgery in combina-tion with radiotherapy, immunotherapy or chemotherapy is used to eradicate cancer cells, however, this treatment option is limited by ... -
Diagnostic value of routine semen analysis in clinical andrology
(Blackwell Publishing Ltd, 2021)Infertility is a major health issue affecting over 48.5 million couples around the world, with the male factor accounting for about 50% of the cases. The conventional semen analysis recommended by the World Health Organization ... -
Proteomics and metabolomics — Current and future perspectives in clinical andrology
(Blackwell Publishing Ltd, 2021)Proteomics and metabolomics are emerging as promising tools to investigate the molecular mechanisms associated with male infertility. Proteins and metabolites play a pivotal role in regulating the molecular pathways ... -
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2021)Oxidative stress is pre-empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ...